Study of insulin secretory response after oral glucose load in smokers
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 5
Abstract
Abstract: The objective is to study of insulin secretory response after oral glucose load in smokers.Study was conducted on normal BMI matched healthy 40 nonsmokers and 60 smokers (divided into 3 groups according to amount of smoking) of age group of 20-50 years. venous blood was drawn after an overnight fasting and fasting blood sugar level, at ½ hour,1 hour , 1 ½ hour and 2 hour after an oral glucose load of 75 gm and Serum insulin estimation (radio- immune assay method) After 75 gm oral glucose load at ½ hour,1 hour , 1 ½ hour and 2 hours interval are estimated. Smokers have relatively increased blood glucose levels and hyperinsulinemia as compared to non-smokers.Smoking is associated with relative glucose intolerance, hyperinsulinemia and a slower insulin response which is independent of age and BMI. The alteration is directly proportional to the amount of smoking. Keywords:smokers, insulin secretary response, fasting blood sugar, OGTT
Authors and Affiliations
Ramesh Kumar Tilwani, Khemlata Tilwani, Priya Jangid, Madhurima Maheshwari
Keywords
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