Study of Lipid Profile in Chronic Kidney Disease Patients of Non Diabetic Etiology and its Relation to Serum Calcium

Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 9

Abstract

Background: Patients suffering from chronic kidney disease are prone to develop diseases related to the cardiovascular system owing to the accelerated rate of atherosclerosis due to a multitude of factors, one of them being the characteristic "atherogenic" lipid profile abnormality that they exhibit. Few studies have pointed out the role of secondary hyperparathyroidism as a contributing factor in the development of the abnormal lipid profile. Aim 1. To study the pattern of lipid profile abnormalities in chronic kidney disease patients of non-diabetic aetiology and to assess the relation between the degree of renal impairment and the extent of alteration of lipid profile. 2. To study the association between the serum calcium and phophorous levels and hypertriglyceridemia. Materials and Methods: 150 patients were carefully selected after assessing their eligibility using the inclusion and exclusion criteria. History, clinical examination and biochemical investigations were performed .Blood for the assessment of lipid profile was collected after a minimum of 9 hours fasting and a light fat free diet on the previous day. Data was analysed using SPSS software. Results: Patients with chronic kidney disease were likelier to have higher levels of triglyceride and lower HDL values and as the stage of CKD progressed, the abnormalities in TGL and HDL values increased. There is a positive correlation between the level of triglycerides and serum phosphorous in both stage 4 and 5 CKD and an inverse correlation between serum TGL and calcium in stage 4.Dialysed patients exhibit no alteration in their lipid profile as compared to non dialysed patients.

Authors and Affiliations

Dr Jose Kunnel Paul

Keywords

Related Articles

In-vivo biological effect of Carica papaya leaf extracts on P-407 induced hyperlipidemic Albino Wistar rats

To determine the biological effect of Carica papaya leaves extracts Poloxamer induced hyperlipidemia. Thirty-five healthy albino rats of the same sexes weighing 150-200g were divided into seven; group given feed and wate...

Socio – Demographic Characteristics and Clinical Findings associated with Prevalence of Intestinal Parasitic Infection in patients attending Tertiary Care Hospital in Lucknow

Intestinal parasites are endemic worldwide and have been described as constituting the greatest single worldwide cause of illness and disease. Intestinal parasitic infections are responsible for considerable morbidity an...

Adverse Drug Reactions in Children Living with HIV/AIDS Receiving First Line ART

Optimal adherence to anti-retroviral therapy can be improved by early detection, differentiation of selflimiting from potentially serious ADRs, and treatment of ADRs. The medical literature contains numerous studies in a...

A Rare Presentation of Chikungunya in Infant- A Case Report

We have discussed about an infant who contracted the disease - Chikungunya, a resident of endemic area. He had high grade fever followed by rash. His serum was tested for both Dengue and Chikungunya fever. In this case,...

Study of Macular Thickness Using Spectral Domain Optical Coherence Tomography in Healthy Indian Subjects

Purpose: To generate normative data for SD-OCT (Topcon 3D OCT 2000) estimated macular thickness in Indian eyes and establish its relation with age sex and refractive error. Materials and methods: In this cross sectional...

Download PDF file
  • EP ID EP528499
  • DOI -
  • Views 72
  • Downloads 0

How To Cite

Dr Jose Kunnel Paul (2017). Study of Lipid Profile in Chronic Kidney Disease Patients of Non Diabetic Etiology and its Relation to Serum Calcium. Journal of Medical Science And clinical Research, 5(9), 28284-28290. https://europub.co.uk/articles/-A-528499