Study of lipid profile in patients with myocardial infarction
Journal Title: Medpulse International Journal of Pathology - Year 2018, Vol 7, Issue 3
Abstract
Background: Myocardial infarction is one of the leading cause of death worldwide Dyslipidemia is been considered to be a risk factor for development of myocardial infarction, Present study is intended to know association of serum lipid profile with myocardial infarction. Objectives: To estimate serum lipid and extended lipid profile in myocardial infarction patients. Results: A total of 187 patients with Myocardial infarction were studied. Age range was 20yrs to 85 yrs, with mean age of the study population was 53.4 yrs (SD =13.1). Peak incidence was seen 50 -59 yrs, 56 (29.9%) followed by 30 -39 yrs, 41 (21.9%) were aged 40 -49 yrs, 40 (21.4%). Among the patients studied 146 (78.1%) were males and 41 (21.9%) were females. Among the 187 patients studied 77 (41.2%) were having blood cholesterol level above 200 mg/dl, 110 (58.8%) were having less than 200 mg/dl. 73 (39%) subjects were having Triglyceride level above 150 mg/dl, whereas 114 (61%) were having less than 150 mg/dl. 127 (67.9%) were having HDL value less than 40mg/dl whereas 60 (32.1%) were having HDL > 40 mg/dl. 116 (62%) were having VLDL value < 30mg/dl whereas 71 (38%) were having VLDL>30 mg/dl. 144(77%) were having LDL values above 100 mg/dl and 43 (23%) were having LDL value less than 100mg/dl.131 (70.1%) were having ApolipoproteinA1 value <120mg/dl and 56 (29.9%) were having value > 120 mg/dl. 90 (48.1%) were having Apolipoprotein B value more than 130 mg/dl and 97 (51.9%) were having value less 130 mg/dl. There was statistically significant (p= 0.02) positive correlation between Apolipoprotein A1 value and HDL value. There was positive correlation seen with Total cholesterol, triglyceride, VLDL and LDL levels with Apolipoprotein B values. Conclusion: In thepresent study dyslipidemia, low Apo A1 and high Apo B have been found to be associated with Myocardial Infarction.
Authors and Affiliations
Mahesh Kumar C H, Gayatri M, Arun Maski
Keywords
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