A clinico-pathological study of urinary bladder epithelial neoplasms in a tertiary care hospital of Konkan region, Maharashtra

Journal Title: Medpulse International Journal of Pathology - Year 2019, Vol 10, Issue 2

Abstract

Background: Urinary bladder cancers are among the top ten reported cancers in India. Early diagnosis leads to prompt treatment as one tends to catch these tumors early in their formative stage. Objectives: 1.To study urinary bladder epithelial-neoplasms with respect to histopathological pattern, grade and stage. 2.To determine the impact of age, gender, clinical presentation in urinary bladder epithelial neoplasms in a tertiary care hospital of Konkan region, Maharashtra. Material and Method: This is a cross-sectional, descriptive, retrospective study. 60 patients with urinary bladder epithelial-neoplasms from 1/10/2015 to 30/9/2018 were studied for age, gender, clinical presentation and histological characteristics. Result: The commonest age-group affected was 50 – 80 years. Male to female ratio was 1.85:1. Most common histological pattern was Urothelial Neoplasms which was present in 96.68% of the patients. Total two cases of Urinary papilloma, three cases of Papillary Urothelial Neoplasm of Low Malignant Potential, two cases of Urothelial neoplasm with squamous differentiation were present. Total 63.79% of patients had low-grade papillary urothelial carcinoma and 36.21% patients had high-grade papillary urothelial carcinoma. 34.4% of patients had muscle-invasive urothelial carcinoma and 65.51% had muscle non-invasive urothelial carcinoma. One case each of Sarcomatoid squamous cell carcinoma and Mucinous adenocarcinoma were observed. Hematuria was the most common presenting symptom (83.33% cases). Conclusion: Majority (65.51%) of cases were having non-muscle invasive urothelial neoplasms. Majority (63.79%) were low-grade urothelial neoplasms. A significant correlation was observed between male gender and tumor grade as well as male gender and tumor stage.

Authors and Affiliations

Shweta Joshi-Warpe, , Bhushan Malhari Warpe

Keywords

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  • EP ID EP591113
  • DOI 10.26611/1051023
  • Views 82
  • Downloads 0

How To Cite

Shweta Joshi-Warpe, , Bhushan Malhari Warpe (2019). A clinico-pathological study of urinary bladder epithelial neoplasms in a tertiary care hospital of Konkan region, Maharashtra. Medpulse International Journal of Pathology, 10(2), 77-82. https://europub.co.uk/articles/-A-591113