Study of skin prick test, total IgE, blood eosinophil and exhaled nitric oxide (FENO) for classifying allergic or non-allergic asthma and for asthma management
Journal Title: JOURNAL OF FUNCTIONAL VENTILATION AND PULMONOLOGY - Year 2018, Vol 9, Issue 29
Abstract
Background. Asthma is a common respiratory disorder, characterized by local infiltration and activation of a variety of inflammatory mediators and cells. In allergic asthma, increased blood or tissue eosinophilia, total concentration or specific IgE, fraction exhaled nitric oxide are frequently reported. Method. It was a prospective study on 67 asthmatic patients. Eosinophil count, IgE concentrations, lung function, and measurements of nitric oxide in exhaled breath (FENO) were done. The patient had positive skin prick test were classified as allergic asthma patients and patients with negative skin prick test were considered as non-allergic asthmatic patients. Results. More than 70% of patients had a history of allergy, in which allergic rhinitis is the most common comorbidity. Positive skin test of Df, Dp and Blomia house dust mites were higher. Total IgE and blood eosinophil level were high than normal limit. FENO concentrations were higher in allergic asthmatic patients. All asthmatic patients had a good response to ICS with moderate to high doses. The asthma control was achieved after 6 months of standard treatment. Conclusion. Asthmatic patients have mainly allergic characteristics with increased inflammatory biomarkers, especially FENO level. Therefore, the use of FENO is useful for management of asthma.
Authors and Affiliations
Sy DUONG-QUY
Endoscopic profile of primary bronchopulmonary cancer of the smoker versus non-smoker in Ouagadougou
Introduction. Our study aims to determine the endoscopic profile of primary bronchopulmonary cancer of smoker versus non-smokers in Burkina Faso in order to improve the diagnostic approach. Methods. This was a retrospect...
Effectiveness assessment of in vivo and in vitro tests for diagnosing the causes of allergic asthma
Background. In vivo and in vitro tests are commonly used in combination to diagnose allergic conditions, including asthma. Objectives. To assess the effectiveness of in vivo and in vitro tests in the diagnosis of allerg...
Study of the diversity of molds and their toxicity for systemic and respiratory health in soybean sauce
Introduction. Aflatoxins are mycotoxins secreted by Aspergillus flavus, which can colonize the respiratory tract and cause fungal rhinosinusitis or bronchopulmonary aspergillosis. A. flavus is the second leading cause of...
Knowledge, attitudes, and practices of physical education and sports teachers on asthma in Lomé
Introduction. The prevalence of asthma is high in schools with a frequent occurrence of crises during sports activities. Physical education and sports (PES) teachers are often the first witnesses of these crises. The obj...
Epidemiological, clinical and factors associated with obstructive ventilatory disorders in patients received at a clinic in Ouagadougou
Introduction. The use of spirometry is essential for the diagnosis and follow-up of chronic respiratory diseases. One of the abnormalities found in patients received for spirometry is obstructive ventilatory disorder (OV...