STUDY ON PRESCRIBING PATTERNS OF ANTIBIOTICS USED IN THE MANAGEMENT OF VARIOUS INFECTIOUS DISEASES IN ANDRAPRADESH
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 7
Abstract
This study examined the pattern of physicians' prescription of antibiotics and its possible effects on infectious diseases as well as physicians' compliance with recommended guidelines. Records of 110 patients (67 males and 43 females) aged 20-89 years (mean: 52.6±14.6) and patients suffering with various Infectious diseases at Krishna Institute of Medical Sciences, over a period of 9 months were randomly selected. Information on antibiotics prescriptions was recorded. The patients were distributed into different age groups. Patients less than 18 years were excluded from the study. Of the 110 patients studied, 6.3% (07) were on monotherapy and 92.7% (102) on combination therapy. Of the patients on combination therapy, 51.81% (57), 34.54% (38) and 6.3% (07) were on 2, 3 and more than three drugs, respectively. The present study reveals that, Dual therapy Cilastin+Imipenem combination was maximally used in the management of various types of Infectious diseases. In triple therapy Ceftrioxone was used frequently along with Cilastin and Imipenem combination, Likewise 57.14 percent of Piperacillin+Tazobactum combination was used with Cilastin+Imipenem combination in patients taking more than three antibiotics. Our results are consistent with the previously observed benefits of antibiotics combination therapy, and demonstrate an apparent higher efficacy of Cilastin+Imipenem monotherapy than dual therapy in various infectious diseases in the study population. Major limitations of this work include its retrospective nature and the inability to determine the actual patients' adherence to therapy.
Authors and Affiliations
M. Preeth , J. Shobana
Keywords
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