PREFORMULATION STUDIES OF CONTROLLED/SUSTAINED RELEASE FORMULATIONS: AN OVERVIEW
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 5
Abstract
Recently, controlled release drug delivery has become the standards in the modern pharmaceutical design and intensive research has been undertaken in achieving much better drug product effectiveness, reliability and safety. Oral Extended release drug delivery medication will continue to account for the largest share of drug delivery systems. The extended release formulations are the type of formulations which will improves the therapeutic index of drug concentration. These formulations make the drug available over extended time period after oral/Parenteral administration. The extended release product will optimize therapeutic effect and safety of a drug at the same time improving the patient convenience and compliance. Prior to the development of these major dosage forms, it is essential that pertain fundamental physical and chemical properties of the drug molecule and other divided properties of the drug powder are determined. This information decides many of the subsequent events and approaches in formulation development.
Authors and Affiliations
Tushar Lathiya , Akhilesh D. , Prabhakara P. , J. V Kamath
Keywords
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