Study on Rational Use of Anti-Diabetic Drugs in Patients with Diabetes and Other Co-Morbidities
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2013, Vol 2, Issue 2
Abstract
India presently has the largest number of diabetic patients in world and has been infamously dubbed as the ‘Diabetic capital of the world’. The study was undertaken to know the prevalence of Diabetic population and to evaluate the prescriptions for rational use of Antidiabetic medications and the management of existing co-morbidities. A prospective-observational study was carried out in General Medicine Department of a private corporate hospital, for a period of eight months. Evaluation of prescriptions was done for rational use of antidiabetic drugs in diabetic patients with other co-morbidities. Patient Information Leaflet, Diabetic food Chart & Diabetic Diary were prepared and given to patients. Therapeutic guidelines was prepared and given to the relevant department. A total 93 diabetic patients were enrolled in the study. In 48% of the diabetic population Hypertension was the major co-morbidity. The major microvascular complications observed include diabetic nephropathy in 12 (12.93%) patients. The major category of antidiabetic drugs prescribed were insulin (64.4%), sulphonyl urea (40.0%) and biguanides (28.9%), α- glucosidase inhibitor prescribed was acarbose (17.8%).Thirty diabetic patients (32.26%) had two co-morbidities followed by 21 patients (22.58%) with one co-morbidity and 16 (17.2%) patients had three co-morbid condition. In patients with diabetes all drugs should be used with both potential risks and benefits in mind. Conversely, the drugs that lower blood sugars by inducing weight loss and lessening insulin resistance, thereby improving glycemic control and the patient’s quality of life need to be prescribed. Pharmacists play a major role in helping the patient maintain control of their disease.
Authors and Affiliations
Sriram. S
Keywords
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