Surgical treatment of cholangiocarcinoma
Journal Title: Postępy Nauk Medycznych - Year 2011, Vol 24, Issue 1
Abstract
Cholangiocarcinoma (CC) is a malignant tumor originating from the biliary epithelium. It was first described by Maxim Fardel in 1840. CC is the second most common primary liver cancer after hepatocellular carcinoma. This represents about 3% of all cancers of the digestive system. Depending on the location and construction there are two types of CC: intrahepatic (Intrahepatic cholangiocarcinoma – ICC) derived from the intrahepatic bile ducts within the liver parenchyma and extrahepatic (Extrahepatic cholangiocarcinoma – ECC), originating from the extrahepatic bile ducts within the hepato-duodenal ligament and the gallbladder. Depending on the location the ECC are divided into the hilar (Klatskin tumor) and peripheral tumors. Klatskin tumor occurs most often and constitutes 60-70% of all CC. Surgical treatment of CC can be radical or palliative. The method of radical surgical treatment of CC depends mainly on the location of the tumor. In ICC partial liver resection without lymphadenectomy is recommended. In Klatskin tumor partial liver resection, cholecystectomy and excision of extrahepatic bile duct, and regional lymphadenectomy is recommended. In the peripheral ECC pancreatoduodenectomy is performed and it has the best prognosis among all types of CC. In some cases of the CC liver transplantation is used. Approximately 50% of patients with unresectable tumors or with a accompanying disease and non-possibility of an extensive resection palliative treatment is only possible to relieve symptoms and improve quality of life. Palliative treatment consists of decompression of jaundice (endoscopic prosthesis insertion, percutaneous transhepatic biliary drainage and surgical biliary drainage). Palliative surgical treatment includes the biliary drainage and biliary-enteric and gastro-intestinal anastomoses.
Authors and Affiliations
Paweł Lampe, Beata Jabłońska
Keywords
Related Articles
- EP ID EP54001
- DOI -
- Views 138
- Downloads 0
Obesity – the condition predisposing to vitamin D deficiency
Obesity is nowaday well recognized as a global epidemic and is associated with various co-morbidities as cardiovascular diseases, diabetes, cancer (prostate, breast and colon cancer). Obese people are also predisposed to...
Zespół Cushinga a choroby układu sercowo-naczyniowego
Przewlekła hiperkortyzolemia związana jest z licznymi powikłaniami ze strony układu sercowo-naczyniowego. Badania populacyjne wskazują na zwiększoną śmiertelność w grupie pacjentów z zespołem Cushinga. Głównymi przyczyna...
Ocena skuteczności leczenia nierówności kończyn dolnych metodami blokowania chrząstek wzrostowych
<b>Wstęp.</b> W pracy przedstawione zostały wyniki leczenia nierówności kończyn dolnych (kkd) metodą Phemistera, skoblami Blounta oraz techniką Metaizeau.<br><b>Mat...
Hereditary breast and ovarian cancer
Familial breast cancer was first recognized in the Roman medical literature of 100 AD (1). The first documentation of familial clustering of breast cancer in modern times was published by Broca, who reported 10 cases of...
Ocena przydatności klinicznej zaburzeń libido w rozpoznawaniu hipogonadyzmu późnego u mężczyzn
<b>Cel pracy. </b>Oceniano związki pomiędzy stężeniem testosteronu, libido oraz zaburzeniami wzwodu u mężczyzn z hipogonadyzmem późnym (LOH) oraz zaburzeniami seksualnymi.<br>&am...