Synchronous Primary Dual Malignancy of Thyroid and Breast: A Case Report
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 4
Abstract
Known triad of primary tumors presenting in a synchronous fashion is a proven entity, as in MEN syndrome, linked with specific genetic alterations. However synchronous occurrence of an invasive ductal carcinoma in the breast and a papillary carcinoma in thyroid is an uncommon event sparsely reported in literature. The present study has dicusses the presentation, evaluation and management of such a case of dual malignancy. We hereby report a case of 55 year old female presenting to us with lump in the left breast which was cytological proven Infiltrating ductal carcinoma. On further evaluation with PET CT uptake study also showed increased uptake in the thyroid, FNAC from was suggestive of malignancy. The patient was subject to Left modified radical mastectomy and total thyroidectomy in the same setting. The patient’s recovery was uneventful and excised specimens were sent for HPE. The breast specimen showed infiltrating ductal carcinoma with SPR grade 3.Histopathology from thyroid nodule revealed the presence of Papillary carcinoma with chronic lymphocytic changes in the surrounding tissue. The synchronous presentation of dual primary malignancy in Thyroid and Breast is a rarely reported event and should be subject to thorough analysis as treatment options are different for two and may need to be managed accordingly.
Authors and Affiliations
Sahni HS, Nagpal N, Goyal V
Keywords
Related Articles
- EP ID EP541760
- DOI -
- Views 147
- Downloads 0
Assessment of Risk Factors of Obesity among the College Students
Background: Obesity has been defined as abnormal or increased fat accumulation. The present study was conducted to assess the risk factors of obesity among study population. Materials & methods: This study was conducted...
A Comparative Prospective Study of Intrathecal Dexmedetomidine-Fentanyl for Labor Analgesia
Background: Pain relief during maternal labor is one of the main goals of maternity care. Combined spinal epidural analgesia is an accepted technique to alleviate labor pain with minimal side-effects to mother and fetus....
Comparative Assessment of Acute and Chronic Urticaria among patients visited in Dermatology Department
Background: Urticaria commonly presents with intensely pruritic wheals, sometimes with edema of the subcutaneous or interstitial tissue. Hence; we planned the present study to assess and compare the acute and chronic urt...
Maternal & Perinatal Outcome in Antepartum Hemorrhage- A Clinical Study
Background: Antepartum hemorrhage (APH) is a major cause of maternal and perinatal morbidity and is considered one of the complications of pregnancy. The present study was conducted to find out the incidence of antepartu...
MEMBRANOUS NEPHROPATHY IN PREGNANCY- A CASE REPORT AND REVIEW OF LITERATURE
Nephrotic syndrome occurs in 0.012-0.025% of all pregnancies. Membranous nephropathy is a major cause of nephrotic syndrome in adults (30-40%). We present a case of idiopathic membranous nephropathy (IMN) diagnosed durin...