Synthesis and antimicrobial screening of some novel quinazolinones and its derivatives
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2017, Vol 4, Issue 3
Abstract
Various novel quinazolinones and quinazolidine dione derivatives were prepared by using anthranilic acid. Anthranilic acid was synthesized by treating phthalimide with sodium hypobromide solution. The synthesized anthranilic acid was treated with urea, thiourea, acetamide and benzamide to give corresponding titled compounds in good yields. The synthesized compounds were characterized by physical properties and spectral studies (IR, 1H-NMR) and tested for antimicrobial activity.
Authors and Affiliations
B. Satya Sree, A. Lakshmana Rao, P. Swathanthra Babu, K. Surya Kiran, K. Vandana
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