Synthesis and Evaluation of Some New Pyrazolo Phenoxy Acetic Acid Derivatves for their Antitubercular Activity

Journal Title: Journal of Pharmaceutical Sciences and Research - Year 2009, Vol 1, Issue 3

Abstract

 The present research work is aimed to synthesize some novel substituted pyrazolo phenoxy acetic acid. The ten new derivatives of phenoxy acetic acid (Scheme) were synthesized during the course of research work.The structures of compounds have been established by means of FT IR, 1H-NMR and elemental analysis. All the compounds were evaluated for anti-tubercular activity Middle brook 7H9 agar medium against H37Rv Strain.Out of ten compounds P1, P2,P6, P7, P8, P10 shown maximum anti-tubercular activity.

Authors and Affiliations

Pattan S. R. , Hullolikar R. L, . Kapadnis B. P. , Dighe N. S. , Dengale S. S. , Ana Nikalje , Nirmal S. A

Keywords

Related Articles

In vitro In vivo comparison of two pH sensitive Eudragit polymers for colon specific drug delivery

 The aim of this study was to develop the polymer coated diclofenac tablet containing superdisintegrant for colonic drug delivery and compare the in vivo performance of two polymers for site specificity. Eudrag...

Synthesis and Biological Evaluation Of Some 2-Substituted Derivatives Of Benzimidazoles

A large variety of 2-substituted benzimidazoles have been found to possess anti-inflammatory, antispasmodic, a ntihistaminic, a ntimicrobial, anticancer, c ycloxygenase inhibitor, and HIV-1 reverse transcriptase inhibit...

Antinociceptive and Anti-Inflammatory Properties of the Methanol Leaf Extract of Argyreia argentea

The present study was carried out to investigate the antinociceptive and anti-inflammatory properties of methanol leaf extract of Argyreia argentea. Antinociceptive properties of the extract were evaluated on the pain in...

Simultaneous spectrophotometric methods for estimation of levocetirizine and pseudoephedrine in pharmaceutical tablet dosage form.

Two methods for simultaneous estimation of Levocetirizine dihydrochloride (LEVC) and Pseudoephedrine hydrochloride (PSEUDO) in two component solid dosage forms have been developed. The methods employ the application of s...

Most commonly plant exposures and intoxications from outdoor toxic plants

Over the past two decades, there has been an increased recognition of the importance of wild plant used as food and as source of micronutrients and plant secondary metabolites. Non-cultivated plants are perceived as im...

Download PDF file
  • EP ID EP102365
  • DOI -
  • Views 106
  • Downloads 0

How To Cite

Pattan S. R. , Hullolikar R. L, . Kapadnis B. P. , Dighe N. S. , Dengale S. S. , Ana Nikalje, Nirmal S. A (2009). Synthesis and Evaluation of Some New Pyrazolo Phenoxy Acetic Acid Derivatves for their Antitubercular Activity. Journal of Pharmaceutical Sciences and Research, 1(3), 63-68. https://europub.co.uk/articles/-A-102365