Synthesis, characterization and antimicrobial activity of multifunctional Graphene oxide - Curcumin scaffold.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 5
Abstract
Graphene oxide plays a vital role in recent trends of chemical reactions thanks to the consisting of multifunctional groups such as COOH, C=O, CHO, C6 H5, OH and Epoxy groups. Graphene oxide has been synthesized from graphene powder by modern hummer’s method. Curcumin was synthesized from turmeric powder. The compounds were purified by column chromatographic technique. Dimethoxy curcumin was bind with the graphene oxide by autoclave method. The structures were determined by UV and IR spectral studies. Anti-bacterial activity of the gram negative bacteria which affects the Urinary tract of the human was carried out by Disk diffusion method. Antibacterial activities of the newly prepared scaffold were compared with the individual curcumin and Graphene oxide. Novel Go- Cur scaffold showed higher efficient its parent compounds.
Authors and Affiliations
G. Elavarasi . , J. Sivasakth . , Dr. M . Amutha, Dr. B. Jeyaprabha, Dr. P. Prakash, Dr. A. Gubendran5
Keywords
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- EP ID EP386641
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