Synthesization of o-amino Benzonic Acid Modified β-cyclodextrin and Palladium Catalyzed Heck Coupling Reaction in Aqueous Media
Journal Title: 河南科技大学学报（自然科学版） - Year 2019, Vol 40, Issue 3
Abstract
Taking o-amino benzonic acid andβ-CD as raw materials, mono- (6-o-amino benzonic acid-6-deoxy) -β-CD was synthesized and characterized by1H NMR and13C NMR.Heck coupling reaction was proceeded with high efficiency in aqueous media by using mono- (6-o-amino benzonic acid-6-deoxy) -β-CD as the ligand and palladium acetate as the palladium source.The effects of catalyst loadings, bases, reaction temperature and reaction time on Heck coupling reaction were explored, and the scope of the substrates was analyzed.The results show iodobenzene can almost be converted totally by utilizing iodobenzene and styrene as substrates, K2CO3as the base, with 0.20%of the catalyst loading, at 130℃for 10 h.Under the optimized reaction conditions, the coupling yields of the substrates can be above 80%and the yields are influenced by the steric hinderance and electronic effect.
Authors and Affiliations
Xinglong ZHOU, Xuming GUO, Huangyi WU, Fangfang JIAN
Keywords
Related Articles
- EP ID EP469113
- DOI 10.15926/j.cnki.issn1672-6871.2019.03.017
- Views 73
- Downloads 0
Brazilian Disc Dynamic Split Test of High Strength Concrete
In order to investigate the dynamic tension strength of high strength concrete,the flattened Brazilian disc specimens were subjected to impact under different projectile speeds by using the 100 mm diameter split Hopkinso...
Potential Drift Compensation Technology of pH Online Monitoring in Deep Aquifer
The long-time and online monitoring of p H was restricted by potential drift. The influence factors of potential drift were discussed in p H long-time and online monitoring, and the critical factors was confirmed.Based o...
Vehicle Real Driving Cycle Construction Based on Improved Fuzzy C-means Clustering Algorithm
Since the performance of Fuzzy C-means ( FCM) clustering algorithm depended on the initial clustering center, the iterative was inclined to fall into the local extremum and could not ensure that FCM converges to an optim...
Two-stage Equalization Charge-discharge Control Strategy for Lithium-ion Battery Pack
Owing to the problems of complex control and inconsistent charge caused by a mass of cells of electric vehicle lithium-ion battery pack, a two-stage equalization topology and control strategy were proposed based on first...
effects of Breaking Time on Oscillation Mechanism of Nonlinear Switched System
1