The antibacterial activity of the traditionally used Cymbopogon schoenanthus and Senna holosericea, collected from Alabwa region, Saudi Arabia
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 2
Abstract
The biodiversity of medicinal plants have many economic importances and improve human health. Many biologically active compounds were isolated from plants that were traditionally used in folkloric medicine . These compounds can be either a new drug or a base for new drug. The antibacterial activity of the traditionally used Cymbopogon schoenanthus and Senna holosericea, collected from Alabwa region, Saudi Arabia was determined using agar well diffusion method. The plants were collected, identified and extracted using both different organic solvents (methanol, ethanol and acetone) and hot water. The tested bacteria were multidrug resistant, Escherichia coli, Micrococcus lutes, Klebsiella pneumonia, and Shigella sonnei. Maximum activity was recorded for the methanolic extract Senna holosericea against all tested bacteria with inhibition zone diameter ranged from 31-35 mm and MIC value of 37.5 µm/ml. Lower activities was recorded for the methanolic extract of Cymbopogon schoenanthus against all tested bacteria with MIC ranged from 37.5 -70 µm/ml. Weak antimicrobial activity or no activities were recorded for hot water extracts of the two tested plants. No toxicity was recorded for the methanolic extracts of the two tested plants using Artemia salina as test organism. In conclusion, the two tested plants, used traditionally in medicine by popular, recorded antimicrobial activities against the multidrug resistant bacteria with no toxicity.
Authors and Affiliations
Magda M. Aly1, Worood A. Al-youbi1, Amal Y. Aldhebiani
Keywords
Related Articles
- EP ID EP388538
- DOI 10.9790/3008-1202024752
- Views 46
- Downloads 0
Antioxidant and Antidiabetic Activity of Aqueous Extract of Myrtus Communis L. Berries on Streptozotocin-Induced Diabetic Rats
Background: Myrtus communis L. (MC) is widely used as an antidiabetic plant in folk medicine. This study aimed to analyze the possible antidiabetic and hepatoprotective effects of MC berries in streptozotocin (STZ)- indu...
Study Of The Role Of Septin12 Gene Expression Of Human Spermatozoa On Infertility
Septins belong to a family of polymerizing GTP-binding proteins that are required for many cellular functions, such as membrane compartmentalization, vesicular traficking, mitosis,and cytoskeletal remodeling.One family m...
Dose Dependent Effects of Retinoids on the Heart of Swiss Albino Mice
The specific branch of developmental biology which deals with abnormalities caused as a result of failure of normal pattern of development is referred as teratogenesis. Retinoids are essential for spermatogenesis, oogene...
Analgesic and Anti-Inflammatory Studies on The Roots Argemone Mexicana Linn(FAMILY: PAPAVERACEAE)
Analgesic and anti inflammatory studies of the ethanol extract of the roots of A. mexicana were studied in mice and rats respectively. Acetic acid-induced writhing in mice and hind paw oedema in rats were determined. The...
Bacterial Isolates from Seafood in Scotland
Vibrio spp., Enterobacteriaceae representatives and Listeria monocytogenes were isolated from commercially prepared smoked and fresh Atlantic salmon, smoked and fresh haddock, live mussels and oysters. Isolates were iden...