THE ANTIMICROBIAL EFFECT OF AQUEOUS EXTRACT OF TAMARIND (TAMARINDUS INDICA) LEAVES
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 6
Abstract
This study is comparative-experimental work. It was conducted in National Center for Research (Sudan) during the period from 28th of August to 20th December 2013 to investigate the antimicrobial activity of aqueous extract of Tamarindus indica leaves In vitro using diffusion method. Tamarindus indica belongs to Super division Spermatophytes (Seed plants) of the family Leguminosae (Fabaceae). To evaluate the scientific basis for the use of the plant, The leaves was collected from Acacia Forest Trees in Khartoum and extracted using sterile water as a solvent, the antimicrobial activities of extracts of the leaves was evaluated. Serial concentrations MICs (Minimum Inhibitory Concentrations) of the extract were tested against Bacillus subtilis , Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella paratyphi, Candida albicans and Aspergillus niger then comparing the results obtained with standard antibiotic Gentamicin and antifungal Clotrimazole. Furthermore, the combined effect of the extract with Gentamicin and Clotrimazole was tested. The results indicate that the aqueous extract has promising antimicrobial activity against gram positive, gram negative bacteria and fungi. The MIC shows increase in the zone of inhibition when increasing the concentration. In addition, the combination of extract with Gentamicin showed synergistic effect with Salmonella paratyphi while Gentamicin and Clotrimazole showed antagonistic effect with Pseudomonas ariogenosa and Candida albicans respectively.
Authors and Affiliations
Aram Abuzied| School of Pharmacy, Ahfad University for women, Sudan, Mawadda Adam| School of Pharmacy, Ahfad University for women, Sudan, Abu baker Osman Uro| Centre of science & Technology, Ahfad University for women, Sudan, Rashid Eltayeb Abdalla| School of Pharmacy, Ahfad University for Women, Sudan-Faculty of Medicine, Shendi University, Sudan, Amel Ali Suleiman| Centre of Science & Technology, Ahfad University for women, Sudan
Keywords
Related Articles
- EP ID EP3475
- DOI -
- Views 369
- Downloads 17
CYTOTOXIC, ANTIMICROBIAL AND ANTIVIRAL EVALUATION OF THE AERIAL PARTS OF SORGHUMVIRGATUMHACK
Sorghum virgatum (Hack) belongs to Poaceae (Graminae) family, which represented in flora of Egypt by four species. It worth noting that nothing was reported about phytochemical and biological investigation of S.virgatum....
NOVEL SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF SCHIFF BASES OF KETOPROFEN HAVING HETEROCYCLIC MOIETY
A new series of two Schiff bases of ketoprofen having heterocyclic moiety have been synthesized in present investigation. We have tested the anti-inflammatory activities of the synthesized compounds in vivo by using carr...
SEROPREVALENCE OF PARVOVIRUS B19 AMONG SUDANESE PATIENTS WITH SYSTEMIC LUPUS ERYTHMATOSUS
Background Parvovirus B19 is a human pathogen that may result in spectrum of clinical features range from subclinical infection to potentially fatal effects. To the best of our knowledge, there was no study published in...
COMPARATIVE IN VITRO ANALYSIS OF PHYSICOCHEMICAL PROPERTIES OF SOME ACECLOFENAC GENERIC TABLETS MARKETED IN BANGLADESH
Aceclofenac is a non-steroidal anti-inflammatory drug analog of diclofenac and works by inhibiting the action of cyclooxygenase (COX) that is involved in the production of prostaglandin (PG) and accountable for pain, swe...
Influenza Virus Co-Circulation and Emergence of New Variants.