The challenge of finding Chinese blood groups
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 10
Abstract
Up to now, hundreds of human blood groups have been detected globally, but none have been found in the Chinese population. China is a multi-ethnic country with rich genetic polymorphism and variation. The Chinese pangenome reference reveals that the Chinese carry some genetic variations that are different from other ethnic groups in the world, especially the discovery of approximately 5 million new base pair sequences, which are considered the core genome sequences of the Chinese population. Research on red blood cell membrane proteomics has shown that red blood cells carry over 2 600 kinds of erythrocyte membrane proteins, and currently only 37 protein molecules have detected blood group antigens. The above data suggest that the possibility of new blood group in the Chinese population cannot be ruled out. This comment describes the history of the discovery of blood groups and the challenges faced by Chinese scholars.
Authors and Affiliations
Tongmao ZHAO
Keywords
Related Articles
- EP ID EP738652
- DOI 10.13303/j.cjbt.issn.1004-549x.2023.10.001
- Views 6
- Downloads 0
Study on transfusion-related acute lung injury caused by HLA-Ⅱ antibody
Objective To explore the risk factors of transfusion-related acute lung injury (TRALI). Methods The clinical symptoms, signs, imaging examinations, and laboratory test results of two patients with TRALI after blood trans...
Hemolytic disease of the newborn caused by anti-c in puerperant of Asian-type DEL treated by transfusion: a case report
Objective To explore a transfusion therapeutic plan for hemolytic disease of the newborn(HDN) caused by anti-c antibodies in mother of Asian-type DEL. Methods The ABO blood type and Rh phenotype of the mother and child w...
Diversity of IgG autoantibodies of 4 Chinese intravenous immunoglobulins
Objective To develop methods to display the IgG autoantibody repertoire of intravenous immunoglobulin (IVIG) products, analyze the different types of antibodies and study the diversity of IgG autoantibody in 4 IVIG prepa...
Clinical blood dispatching between hospitals in Shijiazhuang
Objective To analyze the blood dispatching of hospitals in Shijiazhuang area, in order to provide reference for blood dispatching policy of hospitals and ensure clinical blood supply. Methods The hospital blood dispatchi...
Survey of knowledge acquisition for blood transfusion of medical staff in Wuwei: an underdeveloped city in western China
Objective To investigate the knowledge acquisition status for blood transfusion of transfusion related medical staff in underdeveloped cities in western China and explore its influencing factors. Methods A questionnaire...