The Comparsion of Piperacillin / Tazobactem with Clindamycin in Diabetic Foot Ulcers
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2013, Vol 2, Issue 2
Abstract
To evaluate and compare the study and efficacy of piperacillin/tazobactem with clindamycin in diabetic foot ulcer according to Wagner’s different grades of classification of diabetic foot ulcer. The study was conducted in department of surgery, Rajah Muthai Medical College and Hospital, Annamalai University, Chidambaram. The study period is from August 2011-January 2012.A total of 100 patients were included in the study were divided in to two groups first group includes the patients treated with piperaciilin/ tazobactem and second group treated with clindamycin. The safety and efficacy outcome was described according to Wagners classification of diabetic foot ulcer. The patients with complaints of diabetic foot ulcer in between the age 20 and 80 and belonging to ulcer grade 2,3,&4 are included in the study and with an ulcer grade 0,1&5 and age below 20 and above 80 were excluded. The study shows that 38% of patients suffering with diabetes mellitus over 10 years and maximum number of patients attended with the ulcer foot were in the age group with 51-60 years followed by 61-70 years. Male population is predominant in the study than female. Piperacillin/tazobactem is more effective than clindamycin for the stabilization of infection in diabetic foot ulcer for supporting the result statistical analysis on ‘t’ test was done
Authors and Affiliations
B. Anil kumar| Department of pharmacy practice, Annamalai University, Annamalai nagar, Tamilnadu., T. Adiveni| Department of pharmacy practice, Annamalai University, Annamalai nagar, Tamilnadu., N. Charan| Department of pharmacy practice, Annamalai University, Annamalai nagar, Tamilnadu., P. Padmini| Department of pharmacy practice, Annamalai University, Annamalai nagar, Tamilnadu., K. Ashwini| Department of pharmacy practice, Annamalai University, Annamalai nagar, Tamilnadu., K. Haritha| Department of pharmacy practice, Annamalai University, Annamalai nagar, Tamilnadu., D. Surya Chandra*| Department of pharmacy practice, Annamalai University, Annamalai nagar, Tamilnadu., Dr. N. Junior Sundresh| Department of surgery, Asst. medical superintendent, RMMCH, Annamalai University, Annamalai nagar, Tamilnadu.
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