The Effect and Mechanism of Lithium Carbonate on Bipolar Disorder and its Immunological Contributions
Journal Title: Journal of Regenerative Medicine & Biology Research - Year 2023, Vol 4, Issue 1
Abstract
Bipolar disorder is a mental disorder that affects hundreds of thousands of people worldwide. Common treatment options are cognitive, behavioral, and medicinal treatment, though medicinal treatment is shown to be most effective because the brain is shown to be “damaged.” This damage is evidence based on a significant reduction of gray matter in neural areas that enable and/or regulate bipolar-related symptoms. This is evident in immunological-related responses against the brain during a brain trauma or stroke, and similar clinical values are observed during episodes of psychosis, leading researchers to believe that drug treatment is beneficial to treat the misrepresented neurodegenerative disease. Lithium carbonate is a drug commonly used to treat bipolarism as it is proven to reduce the effects of mania and psychosis as well as serve to be prophylactic against episodes of depression. It is also shown to elevate levels of white blood cells through its influence on signaling pathways within the brain that encourage an increased granulocyte production. Though, as beneficial as it is to treat bipolar-related symptoms and potentially increase the immunological response within the body, its toxicity is quite dangerous in harmful amounts. Current research is now moving forward to continue the investigation of lithium on white blood cells.
Authors and Affiliations
Megha Gupta1, Vincent S Gallicchio1*
Keywords
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- EP ID EP713270
- DOI https://doi.org/10.46889/JRMBR.2023.4102
- Views 42
- Downloads 0
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