The effect of intramuscular injection of spiramycin at therapeutic dose on some blood biochemical and hematological parameters in Assaf sheep
Journal Title: Scientific Journal of Veterinary Advances - Year 2012, Vol 1, Issue 6
Abstract
Spiramycin is used to treatment of different bacterial and protozoal infection in different animal species including sheep, to the authors’ knowledge there are no studies about effects of spiramycin in sheep blood biochemical and hematological parameters. This study was designated to determine the effects of spiramycin intramuscular treatment at therapeutic dose (64,000 IU/kg) for five days in some blood biochemical and hematological parameters in healthy Assaf sheep (n=8). The results showed that spiramycin treatment caused decrease in calcium and creatinine level (P<0.05) without significant change in albumin, total protein, magnesium, glucose and the adjusted calcium level (P>0.05). After treatment, hematological parameters tend to decrease toward normal references range of red blood cell count, haemoglobin concentration, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and red blood cell distribution width (P<0.05). No changes were observed in hematocrit, mean corpuscular volume, platelet count and mean platelet volume (P>0.05). All the measured biochemical and hematological parameters were in the normal references range after the treatment. These results suggested that spiramycin given in therapeutic regimen to healthy Assaf sheep caused only minor inconclusive changes in the measured hematological and biochemical profiles; and thus can be used safely in treating susceptible infections in sheep. These results might be accepted as a starting point for future experiments to evaluate the effects spiramycin on the different systems and parameters.
Authors and Affiliations
I. Al Zuheir*| Faculty of Veterinary Medicine, a Najah National University, Nablus, Palestine., M. Abdaldayem| Faculty of Veterinary Medicine, a Najah National University, Nablus, Palestine.
Keywords
Related Articles
- EP ID EP878
- DOI -
- Views 441
- Downloads 21
Prevalence of giardiasis in cattle slaughtered in Sokoto metropolitan abattoir, Sokoto, Nigeria
The prevalence of Giardiasis in cattle slaughtered in the Sokoto metropolitan abattoir was investigated. Faeces and bile samples were collected and processed using formal-ether concentration technique. The essence of thi...
Expression of the bovine neutrophil β-defensins4 (BNBD4) and 10 (BNBD10), and β-defensin 1(DEFB1) in the bovine mammary gland with chronic mastitis by Staphylococcus aureus
Bovine mastitis is the most costly infectious disease of dairy cattle worldwide and ischaracterized by inflammation of the mammary gland. The etiology of the pathogens influences the severity of the inflammation and the...
Effects of age, rearing system and their interaction on phenotypic characteristics in hisex brown laying hens
The study was conducted in a commercial poultry farm in Quaish under Chittagong district to observe the effects of age and rearing system on phenotypic characteristics Hisex brown layer strains. Several phenotypic charac...
Influence of two substrates on the performances of Archachatina marginata’s adults and juvenile in Benin
Laying performance of 168 breeders and growth rates of 420 juveniles on both substrates (Tectona grandis sawdust and compost) for 12 weeks were determined in African giant snails Archachatina marginata. The experimental...
Effect of garlic (Allium stivum) powder supplementation on growth performance and body measurements in Japanese quail
Experiment was conducted at Avian Research and Training Centre UVAS Lahore in order to observe and identify the effect of different levels of garlic supplementation and a commercial growth promoter on Japanese quail. Fou...