The effect of phototherapy on serum calcium levels in a term neonate
Journal Title: Medpulse International Journal of Pediatrics - Year 2018, Vol 7, Issue 3
Abstract
Phototherapy, exchange transfusion and pharmacological treatment are the main modalities of treatment. Phototherapy plays a significant role in the treatment of hyperbilirubinemia in neonates. Phototherapy may also lead to undesired side effects including skin rash, diarrhea, rise in body temperature, retinal degenerations, nasal obstruction, bronze baby syndrome etc. Nonetheless, no change in blood It is hypothesized that phototherapy inhibits pineal secretion of melatonin which blocks the effect of cortisol on bone calcium. Assuming the probability of type 1 error as 0.05 and a power of 0.8, paired difference to be detected as 0.2 and expected SD of difference from previous study as 0.8, a sample size of 128 was calculated , assuming loss during follow up a total of 150 cases were included in the study. In our study there was decrease in calcium levels in 77.02% neonates, but significant fall to hypocalcemic range was seen only in 2 cases (1.35%). Out of the 2 hypocalcemic neonates both were symptomatic.
Authors and Affiliations
Sachin S Hatti, Charanraj Honnalli, Vinod Uploankar
Keywords
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