The effect of Trachyspermum optical aqueous extract on blood Homeostasis
Journal Title: Journal of Alternative Veterinary Medicine - Year 2017, Vol 1, Issue 1
Abstract
T. capsicum from medicinal herbs is considered as a rich source of thymol with healing properties. Enzymatic coagulation factors stem from the liver. In the present study, 48 adult Wistar male rats were selected and divided randiomly into six groups, including control,witness, and 4 experimental groups. Bleeding time (BT), clotting time (CT), prothrombin time (PT) and activated partial thromboplastin time (PTT) were measured by wounding on the ears, slide and coagulometric methods, using the Dade Behring kits and four-channel-coagulometer, respectively. The resulting values were then analyzed. The results of the measurement of prothrombin time (PT) showed no statistically significant differences in the groups at P≤ 0.05 level. But the measure of activated partial thromboplastin time (PTT) revealed a significant difference between experimental group 2 and the control group. The average time of clotting represented a significant statistical difference in all experimental groups compared to the control group. Moreover, there was statistically significant difference between the mean value of bleeding time of experimental groups 1, 3 and 4 in comparison to the control group (P≤0.05). Based on the findings, it is concluded that an aqueous extract of 400 mg/kg. BW C. capsicum can be used to enhance the speed of coagulation. Since different doses of aqueous extract of T. capsicum show different results on the bleeding time, this extract can be used at low doses to enhance platelet activation and for people who are prone to blood clotting and thus prone to different strokes; the high doses of this extract prevent the formation of unwanted blood clots.
Authors and Affiliations
Mohammad Reza Malizadeh, Ameneh Khoshvaghti, Bijan Akbarpour
Keywords
Related Articles
- EP ID EP711240
- DOI -
- Views 56
- Downloads 0
Inhibitory Effect of Hydroalcoholic Extract of Mint Plant on Escherichia ColiIsolated fromLambs and Goat Kidswith Diarrheain Kazeroun
In spite of advances in the management and prevention techniques as well as strategies for diarrhea treatment, it is still a very common and costly disease affecting the small ruminants. The present study aimed at determ...
New methods of preserving chicken meat
Principles of food preservation means performing processes that protect food against spoilage agents. Food is spoiled by biological agents, chemical and physical reactions. Humans have always used a variety of storage me...
Isolation and molecular Identification of Streptococcus mutans and evaluation of the antimicrobial effect of some herbal plant extracts on them
Introduction and aim: Overuse of antibiotics culminated in increasing of frequency of occurrence of antibiotic resistant bacteria. Therefore, new drugs with minimum complication are needed. Nowadays, herbal drugs as new...
Comparative effect of rosemary hydroalcoholic extract and selegiline on Parkinson's behavioral symptoms
Background and aim: Parkinson's disease (PD) is a neurological disorder that is mainly associated with disruption of dopaminergic neurons in the substantia nigra. Seleglin acts as a neuroprotector to improve Parkinson's...
External Parasitic Worms and Protozoans of the Fish Caught in Shapour River and Seyyed Hossein Spring in Kazerun, Iran
In this study, 38 fish in four species of Shapour River and Seyyed Hossein Spring were caught in 2016, including: Albumus mossulensis, Cyprinion macrostomum, Capoeta barroisi persica and Garra rufa and they were studied...