The influence of collagen from various sources on skin parameters
Journal Title: Engineering of Biomaterials / Inżynieria Biomateriałów - Year 2018, Vol 21, Issue 146
Abstract
Collagen is the main component of connective tissue – it represents 30% of total proteins in the animal body. This protein occurs in a wide range of tissues, e.g. in bone, skin, tendon, ligaments and cornea. It provides structural integrity, strength, resistance to tensile stress and elasticity. Due to its excellent biocompatibility and controlled biodegradability, collagen has found diverse application in the biomedical field such as wound dressing, drug carrier and tissue engineering. However, concerns about contamination of mammalian collagen have stimulated the search of another source of this biopolymer. Fish wastes are thought to be an attractive and safe new source of collagen. Fish and mammalian collagen differ in physical and chemical properties. The aim of this work was to examine the influence of collagen extracted from different sources (rat tail tendons, fish scales of northern pike (Esox lucius) and fish skin of Brama australis) on skin parameters such as hydration, colour, pH and skin’s barrier quality. The measurements had been taken on the skin surface before as well as after application of the collagen solutions. The most harmful effect on skin parameters was observed after application of rat tail collagen solution. Collagen extracted from scales of Esox lucius showed the most favourable effect on the skin parameters. The source of collagen has a significant influence on its effectiveness. The greatest virtues for human body were observed in the case of fish collagen extracted from Esox lucius scales.
Authors and Affiliations
W. Prus, J. Kozlowska
Keywords
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