The Jounced Entrails-Intestine in COVID-19
Journal Title: Journal of Regenerative Medicine & Biology Research - Year 2021, Vol 2, Issue 1
Abstract
Coronavirus disease 2019 (COVID-19), initiated by contemporary coronavirus is a pandemic which engenders severe respiratory disease. SARS-CoV-2 preponderantly transmits through airborne particles and mammoth respiratory droplets additionally, gastrointestinal symptoms are manifested as anorexia, diarrhoea, vomiting, nausea, abdominal pain, hepatic involvement and gastrointestinal haemorrhage. SARS-CoV-2 employs receptors for Transmembrane Protease Serine 2 (TMRPSS2) in order to infect cells in order to engender modifications of Angiotensin Converting Enzyme II (ACE2) within the gut which enhances probability of intestinal inflammation and diarrhoea. Comorbidities such as asthma, hypertension, smoking, Alzheimer's disease, dementia or disease occurrence in male subjects are associated with disease severity, concurrent complications and mortality in COVID-19.
Authors and Affiliations
Anubha Bajaj
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