The role of glutathione peroxidase in physical exercise
Journal Title: Medycyna Sportowa - Year 2009, Vol 25, Issue 5
Abstract
Reactive oxygen species are continuously formed in metabolic processes. They are toxic derivatives of molecular oxygen which is mostly produced in mitochondria. One of the main source of reactive oxygen species is physical exercise, especially of high intensity. Additional source of it are biological and physical factors, such as ionizing radiation and ultrasounds. Intensification of oxygen metabolism depends on the type of and duration of physical exercise, its intensity and condition of the human organism. Accelerated ROS production and homeostasis disorders lead to oxidative stress. Oxidative stress is associated with pathological and physiological circumstances and causes inactivation of some proteins, intensified lipid peroxidation and ATP reduction. People mostly exposed to the negative effect of reactive oxygen species are sportsmen who practice anaerobic forms of exercise e. x. body-builders. Enzymatic and non-enzymatic defense mechanisms against reactive oxygen species attack have been developed in the human body. The enzymes involved in maintaining prooxidant-antioxidant balance are glutathione peroxidases, which catalyze oxidation of reduced glutathione in reaction with hydrogen peroxide and participate in termination of lipid peroxidation. Interchangeable activities of GPX during physical exercise and/or physical training have been noticed. They are observable in skeletal muscles, blood and other tissues. These changes depend on the type of effort, age of the subject and many additional factors including nutritional supplements. Studies performed on animals demonstrate that GPX activity decreases with age in all studied tissues.
Authors and Affiliations
Rafał Kuźniewski, Alina Woźniak, Anna Kaźnica, Romana Joachimiak, Gerard Drewa, Alicja Jurecka
Keywords
Related Articles
- EP ID EP55780
- DOI -
- Views 109
- Downloads 0
ANALIZA WYBRANYCH PARAMETRÓW POSTAWY CIAŁA ZAWODNIKÓW UPRAWIAJĄCYCH SKOKI DO WODY
[b]Wstęp. [/b]W Polsce funkcjonuje kilka ośrodków ukierunkowanych na szkolenie zawodników w skokach do wody. Celem pracy była analiza wybranych parametrów postawy ciała początkujących zawodników uprawiających skoki do wo...
AKTYWNOŚĆ FIZYCZNA W GRUPIE UCZESTNIKÓW PROGRAMU PROFILAKTYKI WCZESNEGO WYKRYWANIA CHORÓB UKŁADU KRĄŻENIA
[b]Wstęp.[/b] Według Światowej Organizacji Zdrowia siedzący tryb życia jest przyczyną większości niepełnosprawności na świecie. Aktywność fizyczna pozwala kontrolować nasilenie pozostałych czynników ryzyka chorób krążeni...
MORPHOLOGICAL AND FUNCTIONAL ASYMMETRY OF THE UPPER LIMBS IN TABLE TENNIS PLAYERS
[b]Background. [/b]Table tennis belongs to asymmetric sport disciplines. The aim of the study was an assessment of morphological and functional differentiation of selected features of the dominant and the non-dominant up...
A role of vitamin D in athletes
Vitamin D is a prohormone which is produced in the human skin upon exposure to the sunlight and delivered exogenously from the diet and/or a recommended dose of supplementation. Maintaining the adequate vitamin D serum s...
THE INFLUENCE OF CHOSEN ASPECTS OF PLAY IN DEFENCE ON THE LEVEL OF EXECUTIVE ATTENTION CONCENTRATION IN MEN'S BASKET-BALL
Background. The authors assessed the realisation of chosen tasks related to play in defence and their influence on executive attention concentration in basketball teams.Executive attention is understood as a system contr...