The Role of Thyroglobulin in the Management of Thyroid Cancers
Journal Title: Nuclear Medicine Seminars - Year 2021, Vol 7, Issue 1
Abstract
Thyroglobulin (Tg), a glycoprotein that is synthesized in normal thyroid, is a significant biochemical marker of residual thyroid tissue or recurrent/metastatic disease in differentiated thyroid cancers (DTC). In this manuscript, the metabolic characteristics of Tg and various Tg assay methods were briefly described. The value of Tg concentration in presurgical evaluation of DTC patients, the diagnostic performance of Tg measurement in fine needle aspiration biopsy wash-outs from suspicious lesions, and the role of postoperative stimulated and supressed Tg values in guiding the decision-making process for therapy options and the outcome of ablation were summarized. The value of Tg in clinical management of patients with DTC was analysed according to recent procedure guidelines including debating issues like follow-up of patients with lobectomy or rare clinical pictures like Tg negative tumors.
Authors and Affiliations
Zeynep Burak, Fatih Tamer, Mine Gümüş
Keywords
Related Articles
- EP ID EP693437
- DOI 10.4274/nts.galenos.2021.0003
- Views 75
- Downloads 0
Quality Control of Magistral (or in House or Smallscale) Produced Radiopharmaceuticals
As it is known, magistral radiopharmaceuticals are suitable for only in house use and are prepared, produced and supplied with a medical prescription for a certain patient in good laboratory practice (GLP) standard by a...
The Role of Radiotherapy in the Management of Bone Metastasis
Radiotherapy (RT) is an effective method used in the management of bone metastases. Goal of the treatment is pain relief, reducing the need for analgesics, as well as prevention of pathological fracture and spinal cord c...
Guideline for Dopaminergic Imaging in Parkinsonian Syndromes
The purpose of this guideline, which is prepared by the neuropsychiatry imaging task group of the Turkey Association of Nuclear Medicine, is to help nuclear medicine physicians in their practice of dopaminergic imaging i...
Acceptance Tests and Quality Control of the Positron Emission Tomography (PET) Systems
Quality control (QC) applications are important for the reliability and accuracy of the results obtained from positron emission tomography (PET) imaging systems in clinical trials. With these applications, exposure of pa...
Nephrourologic Imaging: Yesterday, Today, Tomorrow
Renal function measurement and renal imaging using radionuclidic methods have a long history. Since 1950s, estimation of glomerular function and tubular function were possible using several radiopharmaceuticals. Later, s...