THE STUDY OF COMPARISON OF SUBLINGUAL VERSUS VAGINAL 25 MICROGRAM OF MISOPROSTOL IN INDUCTION OF LABOUR AT TERM
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 12
Abstract
BACKGROUND Labour is the process by which the products of conception, when they have reached full term or nearing it, are expelled by the mother. Induction of labour implies the artificial initiation of uterine activity to affect labour and delivery. The aim of successful induction is to achieve vaginal delivery with a safe maternal and perinatal outcome and to eliminate any anticipated adverse outcome associated with continuation of pregnancy. It should bring about adequate uterine activity sufficient for cervical changes and foetal descent to occur without causing hyper stimulation or fatal compromise. Successful outcome of spontaneous labour is the result of wellcoordinated interplay between upper segments dominant and contracting, lower segment passive and dilating, Misoprostol is having this property. The present study is undertaken to compare the efficacy, safety of sublingual vs. vaginal Misoprostol in induction of labour at term pregnancy. MATERIALS AND METHODS In this randomized control trial, we had selected 100 antenatal women with term gestation admitted in antenatal ward and labour rooms. These cases were randomised into Group A and Group B. Group A included antenatal women receiving 25 μgms of Misoprostol sublingually. Group B included antenatal women receiving 25 μgms of Misoprostol vaginally in the posterior fornix. The dose is scheduled to be repeated once in every 4 hrs., if necessary, that is, if regular uterine contractions have not started within 4 hrs., of first dose. RESULTS Sublingual administration offers an excellent choice to women, particularly to those who were wishing to avoid vaginal administration. Sublingual Misoprostol is an effective alternative to vaginal Misoprostol in induction of labour. Sublingual route of administration was associated with higher incidence of hyperstimulation. Efficacy of both are almost similar in my study. CONCLUSIONS Induction delivery interval with sublingual misoprostol was less in comparison with vaginal misoprostol. In induction of labour with vaginal misoprostol, the rate of caesarean section was more in comparison with sublingual misoprostol. Furthermore, sublingual misoprostol possesses some advantages like convenience of administration.
Authors and Affiliations
Zainab Z. Raja, Jigar K. Thakkar, Megha S. Patel, Jayun J. Joshi, Janki M. Pandya, Hetal Patel
Keywords
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- EP ID EP555688
- DOI 10.14260/jemds/2019/208
- Views 75
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