The trend towards in vivo bioprinting
Journal Title: International Journal of Bioprinting - Year 2015, Vol 1, Issue 1
Abstract
Bioprinting is one of several newly emerged tissue engineering strategies that hold great promise in alleviating of organ shortage crisis. To date, a range of living biological constructs have already been fabricated in vitro using this technology. However, an in vitro approach may have several intrinsic limitations regarding its clinical applicability in some cases. A possible solution is in vivo bioprinting, in which the de novo tissues/organs are to be directly fabricated and positioned at the damaged site in the living body. This strategy would be particularly effective in the treatment of tissues/organs that can be safely arrested and immobilized during bioprinting. Proof-of-concept studies on in vivo bioprinting have been reported recently, on the basis of which this paper reviews the current state-of-the-art bioprinting technologies with a particular focus on their advantages and challenges for the in vivo application.
Authors and Affiliations
Manyi Wang, Jiankang He, Yaxiong Liu, Meng Li, Dichen Li, Zhongmin Jin
Keywords
Related Articles
- EP ID EP678630
- DOI -
- Views 194
- Downloads 0
3D bioprinting of stem cells and polymer/bioactive glass composite scaffolds for bone tissue engineering
A major limitation of using synthetic scaffolds in tissue engineering applications is insufficient angiogenesis in scaffold interior. Bioactive borate glasses have been shown to promote angiogenesis. There is a need to i...
High-precision three-dimensional inkjet technology for live cell bioprinting
In recent years, bioprinting has emerged as a promising technology for the construction of three-dimensional (3D) tissues to be used in regenerative medicine or in vitro screening applications. In the present study, we p...
The trend towards in vivo bioprinting
Bioprinting is one of several newly emerged tissue engineering strategies that hold great promise in alleviating of organ shortage crisis. To date, a range of living biological constructs have already been fabricated in...
Recent cell printing systems for tissue engineering
Three-dimensional (3D) printing in tissue engineering has been studied for the bio mimicry of the structures of human tissues and organs. Now it is being applied to 3D cell printing, which can position cells and biomate...
Utilising inkjet printed paraffin wax for cell patterning applications
We describe a method to prepare patterned environments for eukaryotic cells by inkjet printing paraffin wax onto a substrate. This technique bypasses the requirement to create a master mould, typically required with the...