To Study the Changes in Intraocular Pressure during various Steps of General Anesthesia using Thiopentone Sodium or Ketamine for Induction and Succinylcholine for Neuromuscular Blockade

Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 6

Abstract

Background: Several general and local anesthetic techniques have been employed to try and prevent increase in intraocular pressure during surgery. Interest in general anesthesia for intraocular surgery is relatively recent. Many surgeons now prefer full anesthesia and indeed the increasing scope of ophthalmic surgery demands it. This study was therefore undertaken to know the changes in intraocular pressure, during various steps of general anesthesia using thiopentone sodium or ketamine for induction and suxamethonium (succinylcholine) for neuromuscular blockade. Material and Methods: Sixty patients between the age group of 1-75 years were selected for this study. These patients were divided into two groups –I and II. The patients in groups were given general anesthesia and were operated for either ophthalmic or non – ophthalmic indications. A detailed general examination (including measurement of blood pressure) and systemic examination was done to rule out any systemic disorder which would directly or indirectly affect the measurement of intraocular pressure during the course of the study. Routine blood and urine investigations were done. Results: The mean fall in intraocular pressure after induction as compared to mean baseline intraocular pressure was 2.48±1.32 in group – I. The mean rise in intraocular pressure after induction as compared to mean baseline intraocular pressure was 2.67±2.08 in group-II. This difference in the intraocular pressure after induction in group -I was statistically highly significant as compared to group -II (p<0.01). Conclusions: Thiopentone sodium can be safely used as an inducing agent in any intraocular surgery done under general anesthesia. Ketamine, as far as possible, should be restricted to extraocular ophthalmic surgeries.

Authors and Affiliations

Manjiri V. Deshpande

Keywords

Related Articles

Comparison of Intravenous Clonidine with Intravenous Lignocaine for Attenuation of Endotracheal Intubation Induced Haemodynamic Response

Background: Endotracheal intubation is the standard practice for general anaesthesia inspite of many supraglottic airway devices have arrived. Various drugs have been used till date to attenuate the hemodynamic response...

Effect of Intravenous Esomeprazole Sodium and Intravenous Pantoprazole on Gastric pH in Adults Undergoing Elective General Anaesthesia

Background: General anesthesia predisposes a patient to regurgitation and aspiration of gastric substances into otherwise healthy lungs leading to fatal acid aspiration syndrome. Historically, this syndrome most commonly...

Comparison of Butorphanol and Buprenorphine as an Adjunct to Local Anaesthetic Solution in Supraclavicular Brachial Plexus Block

Introduction: Opioids are well studied adjuncts although the evidence regarding the analgesic benefit of opioid adjuncts remain equivocal. The effectiveness of buprenorphine and butorphanol administered as adjuncts to lo...

A Clinical Comparative Study of Pre-Emptive Analgesia by Intranasally Instilled Ketamine Vs Fentanyl in Endoscopic Nasal Surgery

This study was undertaken for the study of preemptive analgesic effects of intranasal ketamine and intranasal fentanyl in patients undergoing endoscopic nasal surgery. Material and Method: Patients were allocated in one...

Subarachnoid Hyperbaric Bupivacaine and Isobaric Levobupivacaine: A Prospective Randomized Double Blind Comparative Study

Aim: The aim of our study was to compare the efficacy, block parameters and safety profile of intrathecal hyperbaric bupivacaine and isobaric levobupivacaine for urological surgery. Methods: Urological patients who were...

Download PDF file
  • EP ID EP541346
  • DOI 10.21088/ijaa.2349.8471.5618.15
  • Views 94
  • Downloads 0

How To Cite

Manjiri V. Deshpande (2018). To Study the Changes in Intraocular Pressure during various Steps of General Anesthesia using Thiopentone Sodium or Ketamine for Induction and Succinylcholine for Neuromuscular Blockade. Indian Journal of Anesthesia and Analgesia, 5(6), 969-976. https://europub.co.uk/articles/-A-541346