TOTAL PHENOLIC AND FLAVONOID CONTENTS AND ANTIOXIDANT ACTIVITY OF LANTANA CAMARA AND CUCURBITA PEPO (SQUASH) EXTRACTS AS WELL AS GC-MS ANALYSIS OF LANTANA CAMARA ESSENTIAL OILS
Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 1
Abstract
This study aimed to determine total phenolic and flavonoid contents as well as evaluate antioxidant activity of the defatted methanolic extracts of flowers, leaves, stems and certain fractions (dichloromethane, ethyl acetate, n-butanol and water residue) derived from the defatted methanolic extract of Lantana camara and Cucurbita pepo (Squash) leaves besides, the essential oils of L. camara leaves and flowers by using (DPPH, ABTS and TAC assay). The chemical composition of L. camara essential oils was identified by GC-MS analysis. The results exhibited that the defatted methanolic extracts of L. camara (flowers, leaves and stems) have higher phenolic and flavonoid contents as well as antioxidant activity than C. Pepo (Squash) parts. Also, the ethyl acetate fraction of L. camara has the highest phenolic and flavonoid contents as well as the highest antioxidant activity (DPPH; SC50 = 11.82±0.21 μg/ mL, TAC; 290.96±6.71mg eq. ascorbic acid /g extract, ABTS; 94.03±0.25mm Trolox® eq. / 100g extract). There is a positive correlation between the total phenolic and flavonoid contents and the antioxidant activity of the tested extracts or fractions. GC-MS analysis of essential oil of L. camara leaves and flowers revealed the presence of 47 compounds in leaves and 40 compounds in flower. The major compounds in the leaf oil were 7(11) -selinen-4α-ol (14.50%) and cedrenol (6.50%) whereas, the major compounds in flower oil were cedrenol (10.71%) and farnesyl acetone (7.15%).
Authors and Affiliations
Dr. Mortada M. El- Sayed
Keywords
Related Articles
- EP ID EP616997
- DOI -
- Views 204
- Downloads 0
ANALYSIS OF THE MOLECULAR INTERACTION OF LEVODOPA VS. AMINO ACID USING QUANTUM METHOD
The pharmacological treatment of Parkinson's disease through the drug Levodopa (Lev) is used to control the symptoms and signs of it for as long as possible, minimizing the adverse effects. To date, no treatment has demo...
INFERTILITY AND IT'S DIETARY MANAGEMENT
Definition of infertility is a failure to achieve conception by a couple of mature age having normal coitus, during appropriate period of menstrual cycle, regularly, at least for one year. According to WHO, one in every...
AN IMPERATIVE REVIEW STUDY ON CONCEPT OF OPHTHALMOLOGY IN AYURVEDA IN THE PURVIEW OF RACHANA SHARIR (HUMAN ANATOMY)
Ophthalmology in ayurveda is a branch of a perfect science strictly based upon ayurvedic principles. With the changing concepts of health and disease and shifting scenario of health needs of the present times, there has...
ASSESSMENT THE EFFECT OF SINGLE NORMAL PREGNANCY ON EXPIRATORY FLOW RATES
Background: Dynamic PFTs are an important tool in the evaluation of the functional as well as fitness state of the respiratory system, also for the assessment of severity of illness. Objective: To assess the effect of si...
ANALYSIS OF THE EFFECT OF LEVODOPA ON NITROGENOUS BASES USING QUANTUM METHOD
L-3,4-Dihydroxyphenylalanine (DOPA) or Levodopa (Lev) has been used since the 1960s and has become one of the most widely used drugs in neurology. Lev is a metabolic precursor drug for dopamine. Its therapeutic and harmf...