Transdermal drug delivery system: - a review on transdermal patch
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2014, Vol 2, Issue 9
Abstract
The main advantage of Transdermal drug delivery system is to bypass the first pass metabolism, avertance of the risk and annoyance of intravenous therapy and of the varied conditions of absorption, like pH changes, gastric emptying time and presence of enzyme. The Transdermal drug delivery scheme is generally used where the other systems of drug administration fail or it is mainly used in edema associates congestive heart failure. The transdermal drug delivery has advantage to deliver medicines via skin to systemic circulation at a predetermined rate and maintain therapeutic concentration for prolong period of time. This review describes the assorted formulation aspects, a variety of excipients, evaluation tests, challenges and drugs explored in the pasture of topical drug delivery.
Authors and Affiliations
Rajesh Asija*| Department of pharmaceutics, Maharishi Arvind institute of pharmacy, Mansarovar, Jaipur-302020, Rajasthan, India, Avinash Gupta| Department of pharmaceutics, Maharishi Arvind institute of pharmacy, Mansarovar, Jaipur-302020, Rajasthan, India, Bhagwan Swaroop Maheshwari| Department of pharmaceutics, Maharishi Arvind institute of pharmacy, Mansarovar, Jaipur-302020, Rajasthan, India
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