Treatment of the irritable bowel syndrome: the role of probiotics
Journal Title: Сучасна гастроентерологія - Year 2018, Vol 0, Issue 2
Abstract
Currently, the irritable bowel syndrome (IBS) ranks first in the chronic bowel diseases. Its prevalence varies 1 to 36 % and is about 7 % at average The problems of IBS diagnosis and treatment remain relevant in the modern gastroenterology, as the quality of life in patients with IBS is significantly reduced; it is lower than in patients with chronic heart failure of the 3 functional class and in patients with rheumatoid arthritis. Diagnosis of IBS is based on three key points: 1) the clinical picture and analysis of the history of the disease; 2) a thorough objective examination; 3) conducting a minimum number of laboratory tests and only if there have strict indications, colonoscopy and other instrumental studies. Since IBS is a multifactorial disease, treatment should be directed to various links of pathogenesis. It is believed that the starting therapy of IBS should be a symptom-oriented aimed at eliminating the most pronounced symptoms. In the 4th Rome Consensus, the use of probiotics is recommended. In a consensus, only one probiotic is mentioned with a specific strain — Bifidobacterium infantis 35624, which in Ukraine is registered as Alflorex. It is indicated that the use of Bifidobacterium infantis 35624 in patients with IBS results in the significant relief of abdominal pain/discomfort, swelling/improvement of defecation disorders. Our limited experience of using this drug is associated with its recent appearance in Ukraine. At the same time, B. infantis 35624 — Alflorex has been successfully used in the USA for more than 10 years and is the strain number 1 as per recommendations of the US gastroenterologists. Thus, the diagnosis and treatment of IBS should be guided by Recommendation IV of the Rome Consensus, which clearly defines the need for probiotics. Use of B. infantis 35624 — Alflorex in patients with IBS is consistent with current international recommendations and is proven by many clinical studies. This drug was studied in detail and demonstrated high clinical efficacy in the treatment of patients with IBS.
Authors and Affiliations
A. E. Dorofeyev, M. M. Rudenko, N. I. Shvetz, T. P. Snisarevska
Keywords
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