TRIOXACARCINS AS A PROMISING CLASS OF ANTICANCER DRUGS
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2019, Vol 8, Issue 10
Abstract
Trioxacarcins are intricate and polyoxygenated natural products with exceptional anti-malarial and antineoplastic flair. Trioxacarcins are extracted disclosing six of their types, namely, trioxacarcin A, B, C, D, E and F. Much valuable work has been executed in the line of synthesis of trioxacarcins and their derivatives keeping brevity of steps and efficiency of reactions in focus. Additional efforts are still requisite in formulation and biological studies of trioxacarcin D, E and F as literature proves efforts made on exploration of A, B and C types mainly. This class has an outstanding feature of covalently binding with DNA duplex, therefore, underlining its prospectives to manipulate genes for impeding serious diseases. Nature encloses remedy for every affliction and trioxacarcins class of drugs is a medicinal treasure for modern world facing agitating health complications like cancer.
Authors and Affiliations
Syeda Khair-ul-Bariyah
Keywords
Related Articles
- EP ID EP669419
- DOI -
- Views 148
- Downloads 0
THE EFFECT OF BEER BRANDS ON SOME RENAL INDICES IN MALE ADULT CONSUMERS IN PORT HARCOURT, NIGERIA
Background: It is thought that immoderate consumption of beer among consumers could have adverse effects on the kidney. Objectives of the study: The effect of beer brands on some renal function indices was investigated i...
IN VITRO INVESTIGATION OF ANTIBACTERIAL AND ANTILEISHMANIAL ACTIVITIES OF GUM-RESIN OF BOSWELLIA SERRATA USING (0.5%) DMSO SOLUTION AS AN ALTERNATIVE SOLVENT FOR EXTRACTION
Boswellia serrata belongs to the family Burseraceae, is a plant that produces frankincense. The plant is native to India and extends to Pakistan. The tree yields oleo-gum- resin which has been used for a variety of thera...
CHOLESTEROLEMIC AND ANTIOXIDANT EFFECTS OF EXTRACTS OF SOME LOCALLY CONSUMED FRUITS IN MAIDUGURI
The study assessed the in vitro antioxidant potential of Cucumis sativus, Solanum macrocarpon and Solanum aethiopicum and cholesterolemic effect of Solanum macrocarpon ethanolic extract in in vivo models. The antioxidant...
HEPATOPROTECTIVE ACTIVITY OF SHARBAT CHYLOSIN A POLYHERBAL FORMULATION AGAINST CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS
Carbon tetrachloride (CCl4) is the most commonly used hepatotoxin agents in the experimental studies for evaluate hepatoprotective activity. The present study was designed to evaluate the hepatoprotective activity of Sha...
AN ANALYSIS OF CYBER CRIME AND INTERNET SECURITY
This objectives study is to be review the issues involved of internet security and cyber crime. Apparently this possessed a paradox since the technological advances made in both of software and hardware to increased inte...