Use of Proton Pump Inhibitors – A drug utilization study
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2016, Vol 3, Issue 2
Abstract
Background: In 2006 PPI was the third most frequently prescribed drug in Australia. In United States, UK and New Zealand similar trends were observed. Utilization of proton pump inhibitors is increasing continuously. Differential drug utilization of PPIs are observed along with NSAIDs with antibiotics, Utilization of PPI alone is less, and some newer adverse drugs reactions are being reported, so we planned a study to find out the actual burden of PPI in our area. Methods: 50 registered pharmacies were selected. Then data collection was done after consent of patient or relative having PPI containing prescription and photos of prescription were taken, without any personally identifiable information of patient or physician. Results: 1466 prescription containing PPI were obtained during study. (69.85%) prescriptions were containing NSAIDs along with the PPI. while 55% AMA were used by the physician during the study period. PPI is preferred and prescribed as gastroprotective agents alone or along with antimicrobials and NSAIDs, thus they will reduce the gastrointestinal adverse effects, of concomitant drugs. Conclusion: 45.05% burden of PPI is there in study area observed. PPI are mostly used along with NSAIDs and/or AMA, for their ability to produce gastro protective effect. But their contribution towards adverse effect is to be evaluated.
Authors and Affiliations
Shabbir Rafik Pendhari, Kedar Shashikant Joshi, Ramchandra Prabhakar Limaye
Keywords
Related Articles
- EP ID EP240601
- DOI -
- Views 93
- Downloads 0
Anaphylaxis to parenteral ciprofloxacin in mother leading to foetal death
Anaphylaxis is a rare condition during ante natal care since most of the drugs except nutraceuticals are avoided in pregnancy unless essentially required to prevent developing foetus from any teratogenic effects. An anap...
Adverse drug reactions in patients on aspirin therapy with concomitant antihypertensive medication in a tertiary care hospital of deccan plateau
Introduction To know adverse drug reactions when Aspirin is prescribed with Antihypertensive medicationsMaterials and MethodsProspective observational study conducted in a tertiary care hospital total 60 patients of age...
Attenuation of depressant activity by ethanol extract of seeds of areca catechu in swiss albino mice after deca - days administration
Depression is the loss of ability to enjoy life and experience pleasure. The symptoms are constant, ranging from moderate to severe. If untreated, major depression typically lasts for about six months. Some people experi...
Can promethazine in combination with sub-analgesic doses of fentanyl offer an alternative to pethidine in pain management? – An experimental study
Introduction: Narcotics like morphine or pethidine are neither widely prescribed, nor readily available as analgesic drugs. Availability of fentanyl is relatively easier, but has tolerability issues and dependence liabil...
Use of Proton Pump Inhibitors – A drug utilization study
Background: In 2006 PPI was the third most frequently prescribed drug in Australia. In United States, UK and New Zealand similar trends were observed. Utilization of proton pump inhibitors is increasing continuously. Dif...