USING BREWER’S YEAST AND GINGER IN THE MANAGEMENT OF CONSTIPATION-PREDOMINANT IRRITABLE BOWEL SYNDROME: A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2019, Vol 12, Issue 3
Abstract
Objective: The objective of the present study is to confirm and/or prove the beneficial outcomes from using Brewer’s yeast and Ginger in constipation-predominant irritable bowel syndrome (IBS-C) subjects compared to placebo. Methods: A total of 45 patients suffering from IBS-C were enrolled in a double-blind placebo-controlled study as defined by Rome III criteria. Parallel groups were randomly assigned in this study: A placebo group, Brewer’s yeast group, and ginger group, taken daily for 20 days. IBS severity scale and visual analog scale for IBS (VAS-IBS) were used to assess the severity of pain, abdominal distention, and constipation (IBS-C) subjects. The data were measured at 3 times: At 0 time (T0), after 10 days of treatment (T10), and after 20 days of treatment (T20) for the three treatment groups. Results: Intragroup analysis showed a clinically significant reduction in the symptoms of abdominal pain, distention, and constipation, in the Brewer’s yeast group compared to placebo after the 20 days of the study. There was also a significant reduction of abdominal distention and constipation symptoms in the ginger group throughout the study. Conclusion: This study reveals the beneficial effects of Brewer’s yeast and ginger in reducing troublesome gastrointestinal symptoms in subjects with IBS-C and holds the promise to use them in IBS-C patient.
Authors and Affiliations
ZAINAB G AL-JASSIM
Keywords
Related Articles
- EP ID EP603890
- DOI -
- Views 110
- Downloads 0
STUDY ON THE CHEMICAL CONSTITUENTS OF THE ESSENTIAL OIL FROM NYCTANTHES ARBOR-TRISTIS AND ITS MOLECULAR DOCKING STUDIES
Objectives: The objectives of this study were to determine the chemical composition of the essential oil obtained from the flowers of Nyctanthes arbor-tristis (NAT) and to carryout molecular docking studies against three...
ANTIOXIDANT ACTIVITY OF HALOPHILA OVALIS AND HALOPHILA BECCARII (HYDROCHARITACEAE): TWO IMPORTANT SEAGRASS SPECIES OF CHILIKA LAGOON, INDIA
Objective: The present study was undertaken to evaluate the total phenolic and flavonoid content and the antioxidant property of two important seagrass species namely, Halophila ovalis and Halophila beccarii occurring in...
PECULIAR PROPERTIES OF THE PLANT TAXONOMY AT THE HERBARIUMMUSEUM DEPARTMENT PHARMACEUTICAL AND NATURAL SCIENCES FIRST MOSCOW STATE MEDICAL UNIVERSITY NAMED AFTER SECHENOV
Objective: Department of Pharmaceutical and Natural Sciences of Sechenov First Moscow State Medical University offers students herbarium which should be attributed to special herbaria, namely the collection contains medi...
THE ROLE OF PHARMACISTS IN EVALUATING AND INTERVENING THE PATIENTS WITH DIABETIC NEUROPATHY
Diabetic neuropathies is the presence of and/or signs of peripheral nerve dysfunctions in people with diabetes after the exclusion of other causes. The purpose of this study was to estimate the prevalence and risk factor...
OPTIMUM CONDITIONS FOR N-ACETYL GLUCOSAMINE PRODUCTION FROM TIGER SHRIMP (PENAEUS MONODON) SHELL BY SERRATIA MARCESCENS
Objective: The aim of this research was to determine the optimum condition for Serratia marcescens to produce optimum amount of N-acetyl glucosamine using chitin isolated from tiger shrimp (Penaeus monodon) shells.Method...