Vitamin D and respiratory tract
Journal Title: Postępy Nauk Medycznych - Year 2012, Vol 25, Issue 3
Abstract
Vitamin D plays an important role in the modulation of innate immune system function and the body’s response to microorganisms. It takes an active part in the production of natural antibiotics which are also called natural antimicrobial antibiotics (PAD) using Toll-like receptor pathway (TRL) present on monocytes and macrophages. The antimicrobial antibiotics produced through vitamin D include defensins and cathelicidins.<br>Natural antibiotics contain in its genome sequence VDRE linking the vitamin D receptor (VDR) on the basis of published studies effects of vitamin D in various respiratory diseases is well known. The first single disease research in this context was tuberculosis, we now know that vitamin D is important in the treatment of the other respiratory infections, both bacterial and viral. Many articles are published also on the involvement of vitamin D in the treatment of asthma, COPD, cystic fibrosis. The scientific results sound promising, but still a long way to draw conclusions about doses and use of vitamin D in diseases of the respiratory system and no the specific clinical recommendations. Vitamin D topics are therefore still in the phase of clinical experiments.
Authors and Affiliations
Monika Kuźmińska
Keywords
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