VITAMIN D STATUS IN WOMEN WITH POSTMENOPAUSAL OSTEOPOROSIS

Journal Title: Acta Medica Medianae - Year 2010, Vol 49, Issue 4

Abstract

The perturbation status of vitamin D can be manifested as insufficiency, deficiency and excessiveness. Vitamin D status within the organism is determined by measuring the level of 25(OH)D in the serum. The aim of this paper was to determine the vitamin D status in postmenopausal women with newly diagnosed osteoporosis as well as to correlate vitamin D status with bone mineral density (BMD) and bones' fractures. The research included 58 postmenopausal women who have recently been given the diagnosis of postmenopausal osteoporosis. All the examinees were determined with the level of 25(OH)D as well as the levels of unspecific markers of the bone metabolism. All of the examinees were defined with their bone mineral density on the lumbar spine and hip, measured with DEXA densitometer. The average age of the examinees was 60,46±6,55 years, average duration of menopause 15,02±9,25 years and average concentration of 25(OH)D 46,45±14,68 nmol/L. Our results has shown the deficiency of vitamin D in 89,76% of the examinees with postmenopausal osteoporosis, positive correlation of the level of 25(OH)D and bone mineral density (BMD) and a significantly lower initial concentration of 25(OH)D with the examines with prior bone fractures opposed to those without fractures (37,57±13,08 vs. 51,22±17,26 nmol/L; p<0,02). The obtained results show that vitamine D deficiency in postmenopausal women with osteporosis present important risk factors for bones fractures as well as factors for decreasing the bone mineral density.

Authors and Affiliations

Saša Milenković, Aleksandar Dimić, Aleksandra Stanković, Ivana Aleksić, Dejan Petrović

Keywords

Related Articles

JUVENILE GIANT FIBROADENOMA MAMMAE - CASE REPORT

Fibroadenoma mammae is a mixed fibroepitelioma benign breast tumor caused by proliferation of epithelium and fibrovascular stroma. It makes 7% of all nodular breast changes. Most often, it occurs in women aged 30 to 40 y...

UTICAJ SOCIJALNE PODRŠKE NA TEŽINU POSTTRAUMATSKOG STRESNOG POREMEĆAJA

Poslednja decenija 20. veka, sa poznatim dešavanjima na prostoru bivše SFRJ, imala je za posledicu povećan broj obolelih od posttraumatskog stresnog poremećaja (PTSP). U našem istraživanju pokušali smo da utvrdimo da li...

VALIDACIJA ANALITIČKE PROCEDURE KARVEDILOLA ZA PRIMENU U POPULACIONOJ FARMAKOKINETIČKOJ ANALIZI

Karvedilol je neselektivni beta/alfa-1 blokator koji se koristi za lečenje hipertenzije, hronično stabilne angine i nestabilne angine pectoris, kao i ishemijske disfunkcije leve komore. Cilj ovog rada bio je da se opiše...

ELIMINACIJA INHIBITORA ANGIOTENZIN KONVERTUJUĆEG ENZIMA PUTEM PERITONEUMSKOG DIJALIZATA

Inhibitori angiotenzin–konvertujućeg enzima (ACE inhibitori) najčešće su propisivani antihipertenzivni lekovi. Iako pripadaju istoj grupi lekova i pokazuju sličnu kliničku efikasnost, pojedini ACE inhibitori imaju različ...

GASOVI STAKLENE BAŠTE I MERE PREVENCIJE

Efekat staklene bašte se može definisati kao posledica zagrevanja Zemljine površine i niže atmosfere ugljen-dioksidom, vodenom parom i drugim gasovima koji se nalaze u tragovima u atmosferi. Opšte je poznato da je ljudsk...

Download PDF file
  • EP ID EP91827
  • DOI -
  • Views 116
  • Downloads 0

How To Cite

Saša Milenković, Aleksandar Dimić, Aleksandra Stanković, Ivana Aleksić, Dejan Petrović (2010). VITAMIN D STATUS IN WOMEN WITH POSTMENOPAUSAL OSTEOPOROSIS. Acta Medica Medianae, 49(4), 16-18. https://europub.co.uk/articles/-A-91827