Vivax-induced thrombocytopenia may be associated with lymphopenia and mild anaemia. Correlation of RBC parameters with WBC and platelet counts – A report of 13 patients with vivax malaria
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 8
Abstract
Present study relates to the results of haematological investigations of 13 patients with vivax malaria. One of the 13 patients had moderate anaemia. Eight other patients had mild anaemia. Four other patients had normal haemoglobin (Hb) concentration. Leucopenia was detected in two patients. Three patients had lymphopenia. Two other patients developed mild eosinophilia. Thrombocytopenia was detected in 12 of 13 patients (92%). Three patients had severe thrombocytopenia (platelets <0.5 lac/mm3 ). Six patients had moderate thrombocytopenia (platelets 0.5 lac to <1 lac/mm3 ). Three other patients had mild thrombocytopenia (platelets 1 lac to <1.5 lac/mm3 ). Thrombocytopenia might have developed subsequent to bone marrow suppression of megakaryocytes or due to platelet sequestration by splenic macrophages. In patients, results of product moment correlation (r) revealed direct correlation between Hct and neutrophil count (r = 0.932) and between MCHC Vs neutrophil count (r = 0.467). In addition, inverse relation was detected between MCV vs WBC (r = - 0.523) and between MCV vs neutrophil count (r = - 0.382). These observations suggested that Hct, MCHC and MCV all might affect neutrophil count in malaria.
Authors and Affiliations
Akansha Singh
Keywords
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