WEREWOLF SYNDROME –An Orphan Genetic Disorder
Journal Title: International Journal of Pharma Research and Health Sciences - Year 2017, Vol 5, Issue 2
Abstract
Hypertrichosis is expressed as a genetic disorder in which hair follicles that react to androgens. This will allow for the heaviness of the hairs and rate of growth to increase. There are many other different causes for a person to develop this orphan disorder like congenital hypertrichosis and acquired hypertrichosis. The overall cause of hypertrichosis for the most part is unknown. Scientists consider that hypertrichosis is a form of genetic disorder that arise due to a spontaneous mutation in the DNA sequence. However, some studies have shown that the mutation leading to congenital generalized hypertrichosis (CGH) is located between q24-q27 regions of the X-chromosome. There are many affordable and convenient treatment options for hypertrichosis.They include shaving, trimming, plucking, bleaching, waxing, chemical depilatories, electrosurgical epilation, and tropical eflornithine. Recently, laser hair removal has been proposed as a treatment option. It believed to have less side effects and produces a long lasting results.
Management of Acute Renal Failure
Acute renal failure is the generic term for an abrupt and sustained decrease in renal function resulting in retention of nitrogenous (urea and creatinine) and non-nitrogenous waste products. Depending on the severity and...
Formulation and Evaluation of Taste Masked Orodispersible Tablet of Naproxen Sodium
Objective: The aim of present work is mask the bitter taste of Naproxen sodium and formulate orodispersible tablets of Naproxen sodium. Experimental work: The bitter taste of drug was masked by using Ion exchange resin o...
Development and Validation of RP-HPLC Method for Simultaneous Estimation of Levosulpiride and Pantoprazole in Combined Pharmaceutical Dosage Form
The objective of present work was to develop and validate a simple, accurate,precise HPLC method for the estimation of levosulpiride and pantoprazole. The chromatographic separation was achieved on a Hypersil BDSC18colum...
Phytochemical Screening and Antibacterial Activity of Chloroxylon swietenia DC.
Objective: Chloroxylon swietenia traditionally used as antimicrobial, antifertility, analgesic, insecticidal, antifeedant in traditional medicine system hence the present work is conducted to evaluate antibacterial activ...
Development and Validation of New Analytical Methods for the Estimation of Ritonavir in Bulk and Pharmaceutical Dosage Forms
Pharmaceutical analysis occupies a pivotal role in statuary certification of drugs and their formulations either by the industry or by the regulatory authorities. The current good manufacturing practices (CGMP) and the F...