Zmiany czynności mioelektrycznej żołądka u osób z depresją i objawami dyspeptycznymi
Journal Title: Folia Medica Lodziensia - Year 2016, Vol 43, Issue 1
Abstract
Introduction: A chronic or recurrent pain and discomfort in the upper abdomen occurs frequently in depressive patients. The pathogenesis of these symptoms is complex and not fully understood. The aim of the study was to estimate the gastric myoelectrical activity in this group of patients. Material and methods: The study group consisted of 90 subjects, including 71 women and 19 men (mean age – 38.0±8.1). Among them three groups were divided: healthy subjects (K, n=30), depressive patients with dyspepsia (group II, n=30) and depressive patients with Helicobacter pylori infection (group III, n=30). All the subjects completed Hamilton Depression Scale and the gastric myoelectrical activity examination with Polygraph–Medtronic A/S (Denmark) was done before and after a liquid meal for 120 minutes. Results: Preprandial normogastria in depressive patients (group II, III) compared to healthy subjects (group K) was lower 79.5±8.1% vs 73.6±8.7% (p<0.01) and 79.5±8.1% vs 68.4±9.9 (p<0.001). The similar differences were recorded during postprandial time. Power ratio scale (PR) was also lower in depressive patients than in healthy subjects: 3.5±0.7 (K), 1.6±0.7 (group II), 1.7±0.8 (group III) – p<0.001, p<0.001 respectively. Conclusions: In depressive patients gastric myoelectrical activity is disturbed and probably causes chronic dyspepsia symptoms
Authors and Affiliations
Paweł Wojtkiewicz, Agnieszka Stępień, Jan Chojnacki
Keywords
Related Articles
- EP ID EP200451
- DOI -
- Views 101
- Downloads 0
Zmiany czynności mioelektrycznej żołądka u osób z depresją i objawami dyspeptycznymi
Introduction: A chronic or recurrent pain and discomfort in the upper abdomen occurs frequently in depressive patients. The pathogenesis of these symptoms is complex and not fully understood. The aim of the study was to...
Rola mesalazyny w chemoprewencji raka jelita grubego
Colorectal cancer (CRC) is the fourth most commonly diagnosed cancer in females and the third in males. Every year there are more than a million new cases of colorectal cancer and more than six hundred thousand patients...
Rola tryptofanu i serotoniny w patogenezie i leczeniu zespołu jelita nadwrażliwego
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder of a very complex etiopathogenesis. There are three clinical types of this syndrome: with constipation, with diarrhea and mixed, with alternating c...
The effect of DNA methyltransferase and histone deacetylase inhibitors on αKlotho gene expression in bladder cancer T24 cell line
Introduction: αKlotho gene was originally identified as a putative agesuppressing gene in mice. Recently it is known that αKlotho gene functions as a tumor suppressor in many types of cancer, including breast, pancreas,...
Przydatność kliniczna i diagnostyczna oznaczeń D–dimeru w różnych stanach chorobowych
There are many methods dedicated to assessing D–dimer. They are divided into two categories: qualitative and quantitative methods. All the methods are based on immunochemical reaction with the use of monoclonal antibodie...