Zmiany czynności mioelektrycznej żołądka u osób z depresją i objawami dyspeptycznymi
Journal Title: Folia Medica Lodziensia - Year 2016, Vol 43, Issue 1
Abstract
Introduction: A chronic or recurrent pain and discomfort in the upper abdomen occurs frequently in depressive patients. The pathogenesis of these symptoms is complex and not fully understood. The aim of the study was to estimate the gastric myoelectrical activity in this group of patients. Material and methods: The study group consisted of 90 subjects, including 71 women and 19 men (mean age – 38.0±8.1). Among them three groups were divided: healthy subjects (K, n=30), depressive patients with dyspepsia (group II, n=30) and depressive patients with Helicobacter pylori infection (group III, n=30). All the subjects completed Hamilton Depression Scale and the gastric myoelectrical activity examination with Polygraph–Medtronic A/S (Denmark) was done before and after a liquid meal for 120 minutes. Results: Preprandial normogastria in depressive patients (group II, III) compared to healthy subjects (group K) was lower 79.5±8.1% vs 73.6±8.7% (p<0.01) and 79.5±8.1% vs 68.4±9.9 (p<0.001). The similar differences were recorded during postprandial time. Power ratio scale (PR) was also lower in depressive patients than in healthy subjects: 3.5±0.7 (K), 1.6±0.7 (group II), 1.7±0.8 (group III) – p<0.001, p<0.001 respectively. Conclusions: In depressive patients gastric myoelectrical activity is disturbed and probably causes chronic dyspepsia symptoms
Authors and Affiliations
Paweł Wojtkiewicz, Agnieszka Stępień, Jan Chojnacki
Keywords
Related Articles
- EP ID EP200451
- DOI -
- Views 104
- Downloads 0
Rola tryptofanu i serotoniny w patogenezie i leczeniu zespołu jelita nadwrażliwego
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder of a very complex etiopathogenesis. There are three clinical types of this syndrome: with constipation, with diarrhea and mixed, with alternating c...
Analysis of polymorphisms / mutations of PTEN, CDKN2A, TP53 genes and of hMSH6 gene in endometrial hyperplasia and carcinoma
Endometrial cancer belongs to the most frequent malignancies in the female genital organs with a growing incidence trend. The molecular changes, which are specific for particular stages of neoplastic transformation or th...
Elektroforetyczna identyfikacja proteinaz cysteinowych w surowicach pacjentów z przewlekłą białaczką limfocytową (PBL) z wykorzystaniem biotynylowanego jodoacetamidu
Introduction: Cysteine proteases are enzymes that regulate numerous physiological and pathological processes in the human body. Disorders of their activity can lead to a number of diseases. They play an important role in...
Zmiany czynności mioelektrycznej żołądka u osób z depresją i objawami dyspeptycznymi
Introduction: A chronic or recurrent pain and discomfort in the upper abdomen occurs frequently in depressive patients. The pathogenesis of these symptoms is complex and not fully understood. The aim of the study was to...
Wyniki leczenia operacyjnego raka nerki w I Klinice Urologii Uniwersytetu Medycznego w Łodzi w latach 2004–2010
Introduction. Aim of the study: The only effective treatment method for all forms of the kidney cancer is surgery with possible subsequent institution of neoadjuvant treatment. The standard management involves nephrectom...