Genetic Polymorphisms of Metabolic Enzymes and the Pharmacokinetics of Indapamide in Taiwanese Subjects Journal title: The AAPS Journal Authors: Teng-Hsu Wang, Cheng-Huei Hsiong, Hsin-Tien Ho, Tung-Yuan Shih, San-Jan Yen, Hui-Hung Wang, Jer-Yuar... Subject(s): Medicine
Physiologically Based Pharmacokinetic Models in the Prediction of Oral Drug Exposure Over the Entire Pediatric Age Range—Sotalol as a Model Drug Journal title: The AAPS Journal Authors: Feras Khalil, Stephanie Läer Subject(s): Medicine
Novel Endogenous Glycan Therapy for Retinal Diseases: Safety, In Vitro Stability, Ocular Pharmacokinetic Modeling, and Biodistribution Journal title: The AAPS Journal Authors: Shankar Swaminathan, Huiling Li, Mallika Palamoor, Walter T. Luchsinger de Obarrio, Dorababu Madhura... Subject(s): Medicine
Novel Lansoprazole-Loaded Nanoparticles for the Treatment of Gastric Acid Secretion-Related Ulcers: In Vitro and In Vivo Pharmacokinetic Pharmacodynamic Evaluation Journal title: The AAPS Journal Authors: Milind Alai, Wen Jen Lin Subject(s): Medicine
Multiscale Tumor Spatiokinetic Model for Intraperitoneal Therapy Journal title: The AAPS Journal Authors: Jessie L.-S. Au, Peng Guo, Yue Gao, Ze Lu, Michael G. Wientjes, Max Tsai, M. Guillaume Wientjes Subject(s): Medicine
A Priori Prediction of Tumor Payload Concentrations: Preclinical Case Study with an Auristatin-Based Anti-5T4 Antibody-Drug Conjugate Journal title: The AAPS Journal Authors: Dhaval K. Shah, Lindsay E. King, Xiaogang Han, Jo-Ann Wentland, Yanhua Zhang, Judy Lucas, Nahor Hadd... Subject(s): Medicine
Lower Exposure and Faster Clearance of Bevacizumab in Gastric Cancer and the Impact of Patient Variables: Analysis of Individual Data from AVAGAST Phase III Trial Journal title: The AAPS Journal Authors: Kelong Han, Jin Jin, Mauricio Maia, John Lowe, Martina A. Sersch, David E. Allison Subject(s): Medicine
Statistical Power Calculations for Mixed Pharmacokinetic Study Designs Using a Population Approach Journal title: The AAPS Journal Authors: Frank Kloprogge, Julie A. Simpson, Nicholas P. J. Day, Nicholas J. White, Joel Tarning Subject(s): Medicine
Pharmacokinetics of Levodopa, Carbidopa, and 3-O-Methyldopa Following 16-hour Jejunal Infusion of Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson’s Disease Patients Journal title: The AAPS Journal Authors: Dag Nyholm, Per Odin, Anders Johansson, Krai Chatamra, Charles Locke, Sandeep Dutta, Ahmed A. Othman Subject(s): Medicine
Highly Stabilized Curcumin Nanoparticles Tested in an In Vitro Blood–Brain Barrier Model and in Alzheimer’s Disease Tg2576 Mice Journal title: The AAPS Journal Authors: Kwok Kin Cheng, Chin Fung Yeung, Shuk Wai Ho, Shing Fung Chow, Albert H. L. Chow, Larry Baum Subject(s): Medicine
Simultaneous Pharmacokinetic Model for Rolofylline and both M1-trans and M1-cis Metabolites Journal title: The AAPS Journal Authors: Mark Stroh, Matthew M. Hutmacher, Jianmei Pang, Ryan Lutz, Hiroshi Magara, Julie Stone Subject(s): Medicine
Nonaqueous Gel for the Transdermal Delivery of a DTPA Penta-ethyl Ester Prodrug Journal title: The AAPS Journal Authors: Yong Zhang, Matthew P. Sadgrove, Katsuhiko Sueda, Yu-Tsai Yang, Erik K. Pacyniak, John R. Kagel, Bre... Subject(s): Medicine
Influences of Organic Cation Transporter Polymorphisms on the Population Pharmacokinetics of Metformin in Healthy Subjects Journal title: The AAPS Journal Authors: Hwa Yoon, Hea-Young Cho, Hee-Doo Yoo, Se-Mi Kim, Yong-Bok Lee Subject(s): Medicine
Dose Selection Based on Physiologically Based Pharmacokinetic (PBPK) Approaches Journal title: The AAPS Journal Authors: Hannah M. Jones, Kapil Mayawala, Patrick Poulin Subject(s): Medicine
Modeling, Simulation, and Translation Framework for the Preclinical Development of Monoclonal Antibodies Journal title: The AAPS Journal Authors: Kenneth T. Luu, Eugenia Kraynov, Bing Kuang, Paolo Vicini, Wei-Zhu Zhong Subject(s): Medicine