A BRIEF INTRODUCTION TO METHODS OF PREPARATION, APPLICATIONS AND CHARACTERIZATION OF NANOEMULSION DRUG DELIVERY SYSTEMS
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 1
Abstract
Nanoemulsions have attracted great attention in delivery of therapeutically active agents since approximately 40% of new chemical entities are hydrophobic in nature and the delivery of these poorly water soluble drugs is a challenge for delivery of drugs. The emulsions and Nanoemulsions differ mainly in the size and shape of the particles dispersed in the continuous phase. The particle size in nanoemulsions is (10-200nm) and those of conventional emulsions are (1-20µm). Nanoemulsions are prepared by high energy emulsification methods like micro fluidic and ultrasonic methods, these methods rupture large micro droplets into nano scale droplets. Oil in water (O/W) and water in oil (W/O) nanoemulsions were prepared by aqueous phase titration method. Nano emulsions can be evaluated for their morphology, droplet size, viscosity, PH, optical clarity, zeta potential, conductivity, transmission electron microscopy and polydispersity. Nanoemulsions find application in controlled drug delivery, targeted drug delivery, nutraceuticals, food products, transdermal and colloidal drug delivery. This article includes preparation, characterization, evaluation and application of nanoemulsions.
Authors and Affiliations
Haritha, Syed Peer Basha, Koteswara Rao P, Chakravarthi Vedantham
Keywords
Related Articles
- EP ID EP33029
- DOI -
- Views 388
- Downloads 0
Topical herbal analgesic and anti arthritic (max-relief) versus Diclofenac in symptomatic treatment of osteoarthritis of the knee: a randomized controlled trial
Osteoarthritis of the knee is common among Saudi Arabian men and women. Oral NSAIDS are most commonly used, however, it often have serious adverse effects especially GI complications. This study is designed to determin...
Design and evaluation of fast dissolving tablet of Mefenamic acid by direct compression technique
The demand for fast disintegrating tablets has been growing during the last decade especially for geriatric and pediatric patients because of swallowing difficulties. Mefenamic acid is mainly indicated for to overcome...
Potential Impact of Nanomaterials in Information and Communication Technologies
Nanomaterials are throwing the doors open to a hyper-tech era in which electronics and information and communication technology (ICT) are going to become ubiquitous. Enormous progress has been made by making a transiti...
DEVELOPMENT AND VALIDATION OF A SIMPLE AND RAPID RP- HPLC METHOD FOR THE DETERMINATION OF METRONIDAZOLE AND NORFLOXACIN IN COMBINED DOSAGE FORM
The present investigation describes about a simple, economic, selective, accurate, precise reverse phase high performance liquid chromatographic method for the simultaneous estimation of Metronidazole and Norfloxacin i...
FORMULATION OF MOUTH DISSOLVING TABLETS OF NAPROXEN
The aim of the present work is to investigate the possibility of preparing mouth dissolving tablet containing naproxen by direct compression method. Basic goals in the development of mouth dissolving tablet are to incr...