FORMULATION OF MOUTH DISSOLVING TABLETS OF NAPROXEN
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 4
Abstract
The aim of the present work is to investigate the possibility of preparing mouth dissolving tablet containing naproxen by direct compression method. Basic goals in the development of mouth dissolving tablet are to increase patient compliance, ease of administration, safety and appropriate dosing. It has perceived faster onset of action as the dosage form is disintegrated prior to reaching the stomach and is ideal for acute diseases like allergies, nausea, and vomiting and particularly applicable to manage breakthrough systems. Direct compression method was used to compress the tablets as it is the easiest way to manufacture tablets and less time consuming. Conventional equipment, commonly available excipients and limited number of processing steps are involved in the direct compression and so manufacturing cost is low. Keeping in view the advantages of this delivery system, in the present study, attempts were made to formulate mouth dissolving tablet.
Authors and Affiliations
Rajesh Reddy K, Nagamahesh Nandru, Desam Asha Latha, Srinivasa Rao Chekuri
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