A case study of dermatosclerosis with features of crest syndrome
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2015, Vol 4, Issue 1
Abstract
Systemic sclerosis (systemic scleroderma or SSc) is a chronic connective tissue disease of unknown etiology that causes widespread micro vascular damage and excessive deposition of collagen in the skin and internal organs, in particular GI tract, lung, heart, and kidney. We report the case of a 55 year old female patient who came to RIMS- GH, Kadapa complaints of cough, difficulty in swallowing, breathlessness since 2 weeks along with numbness of fingers. The patient had an ulcer on the right leg with white crystals; it shows the presence of calcinosis. Radiographic data showed bony erosion of the terminal phalanges and esophageal involvement, these findings indicates CREST syndrome. The biopsy report revealed it as scleroderma. The anti-nuclear antibodies and anti- topoisomerase I antibody tests were confirmed as diffuse cutaneous scleroderma. This case illustrates the clinical manifestations of a diffuse cutaneous scleroderma with CREST syndrome features.
Authors and Affiliations
Dr. M Sureswara Reddy
Keywords
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