A Comparative Study of Dexmedetomidine and Clonidine as an Adjuvant to Local Anesthetics among Patients Given Supraclavicluar Block at Tertiary Care Hospital, Gujarat
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2017, Vol 4, Issue 2
Abstract
Background: When adjuvant is used along with local anaesthetic agents they augment the onset of action, prolong the duration of analgesia and improve quality of block. Nowadays different drugs have been used as an adjuvant with local anesthetics in brachial plexus block to achieve quick, dense and prolonged block. Objective: To evaluate the effects of adding a2 receptor agonist Dexmedetomidine and Clonidine to local anaesthetics in brachial plexus block through Supraclavicluar route in upper limb surgeries. Materials and Methods: The present study was conducted on 100 patients of 18 to 60 years age group of either sex of ASA physical status I or II planned for upper limb surgery. According to the adjuvant along with anaesthetic agent given to the patients; they were randomly divided into two groups of 50 patients each. Group A received Dexmedetomidine while in Group B; Clonidine was used as an adjuvant to local anesthetics. Supraclavicluar brachial plexus block was performed according to the group selected. All patients were observed for onset and duration of sensory and motor block, duration of analgesia, VAS score. Results: In Group A Mean age of patients was 35.64 years while in group B,it was 37.48 years. The average duration of surgery was 139.6 minutes in Group A while 147.2 minutes in Group B. Dexmedetomidine (3.5 mins, 6.48 mins) and Clonidine (4.2 mins, 6.48 mins) has similar onset of sensory and motor block time respectively. Both have longer motor block duration than sensory block duration. Dexmedetomidine has significantly prolonged sensory and motor block duration than clonidine (p<0.0001). Dexmedetomidine also has longer duration of analgesia in compared to clonidine withp<0.0001. Conclusion Dexmedetomidine has better profile in terms of duration of sensory and motor block and duration of analgesia, as an adjuvant to supraclavicular brachial plexus block in comparison of clonidine.
Authors and Affiliations
Parikh Aakash A.
Keywords
Related Articles
- EP ID EP466403
- DOI 10.21088/ijaa.2349.8471.42(pt-II)17.23.
- Views 112
- Downloads 0
Comparison of Ultrasound and Anatomic Landmark Guided Techniques for Internal Jugular Vein Cannulation
Background and Objectives: Central venous cannulation is standard of practice in cardiothoracic surgeries for hemodynamic monitoring, administration of fluids and drugs, pacing and so on. The internal jugular vein (IJV)...
Comparative Evaluation of Intravenous Granisetron Hydrochloride and Intravenous Lignocaine Hydrochloride to Alleviate the Pain on Propofol Injection
Propofol is one of the most commonly used induction agent. Pain on injection still remains a considerable concern for anaesthesiologist. The aim of the study was to assess the efficacy of granisetron HCL and ligocaine HC...
Study of Effect of Ondansetron in Preventing Hypotension Following Spinal Anaesthesia in LSCS
This randomized double blind study was conducted to know the efficacy of ondansetron as prophylactic agent for reduction in incidence of hypotension and bradycardia in patients undergoing caesarean section under spinal a...
Comparative Study of Intravenous Ondansetron and Dexamethasone for Amelioration of Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Background: Postoperative nausea and vomiting (PONV) is considered most unpleasant experience by the patients in postoperative period. In particular, following laparoscopic procedures the incidence of PONV is very high....
A Comparison between Etomidate and Propofol for Sedation in Colonoscopy
Propofol has been the widely used sedative agent for colonoscopy.However, in elderly population, propofol causes an exaggerated cardiorespiratory depression. Etomidate causes sedation with minimal effect on cardiovascula...