A Review on Analytical Methods for Determination of Guaifenesin Alone and In Combination with Other Drugs in Pharmaceutical Formulations
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2017, Vol 3, Issue 3
Abstract
Abstract: Guaifenesin is an expectorant and it is use to treat cough and congestion caused by the common cold, bronchitis, and breathing illness. The drug is official in Indian Pharmacopoiea, British Pharmacopoeia, and United States Pharmacopoeias. This article reviews the different analytical methods available for detection of Guaifenesin alone and in combination from various pharmaceutical formulations. They are many analytical techniques have been reported for simultaneous estimation of Guaifenesin and its combined pharmaceutical dosage form but only fewer methods have been reported for estimation of Guaifenesin alone. Some of those techniques are UV spectrophotometry, high-performance liquid chromatography (HPLC), high-performance thin layer chromatography (HPTLC), liquid chromatography - mass spectrometry (LC-MS), gas chromatography (GC), and ultraperformance liquid chromatography (UPLC). Amongst, various analytical methods are available for the quantification of single and multicomponent dosage forms. Keywords: Guaifenesin, Spectrophotometry, Chromatography, Expectorant, Pharmaceutical formulations
Authors and Affiliations
Prayas Acharya, T Prasanth Kumar, Immanuel Agasteen, Sreerama Rajasekhar, G Neelima
Keywords
Related Articles
- EP ID EP390310
- DOI -
- Views 121
- Downloads 0
Perception and Knowledge toward Breast Cancer Prevention and Early Detection: A Comparison between Saudi and Sudanese
The study undertaken the assessment of awareness and specific knowledge, perceived susceptibility, perceived seriousness of breast cancer and perceived benefits of screening for early detection and treatment of women in...
Acute and Subacute Toxicity Study of the Combination of Aqueous Extracts of the Trunk Bark of Musanga cecropioides R. Br. (Cecropiaceae) and the Fruits of Combretum micranthum G. Don (Combretaceae)
The main objective of the work was to evaluate the acute and subacute toxicities of the combinated of aqueous extracts of the bark trunk of Musanga cecropioides and the fruit of Combretum micranthum. The respective extra...
A Case of Minocycline Induced Buccal Mucosa Hyper pigmentation
Abstract: We present a patient exposed to minocycline for 3 years for treatment of resacea, presenting with disfiguring buccal mucosa hyper pigmentation. Discontinuation of the minocycline resulted in dramatic improvemen...
Dengue Outbreak in Eastern part of the Sri Lanka, Study Conducted in Teaching Hospital Batticaloa, Sri Lanka
Abstract: SriLanka is a south-Asian island of Indian Ocean and situated south-east of the Indian subcontinent. Itis in the grip of a severe dengue epidemic. Currently, dengue fever [DF] and dengue hemorrhagic [DHF] fever...
A Study on Litseamonopetala for Evaluation of Pharmacological Activities
Abstract: The aim of this study was to evaluate the cytotoxicity, thrombolytic, anthelmintic and antioxidant activity of mehanolic extract of Litseamonopetala(Family: Lauraceae) leaves in laboratory using in vitro method...