A review on biotransformation
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2014, Vol 2, Issue 2
Abstract
Biotransformation means chemical alteration of chemicals such as nutrients, amino acids, toxins, and drugs in the body. It is also needed to render nonpolar compounds polar so that they are not reabsorbed in renal tubules and are excreted. Biotransformation of xenobiotics can dominate toxic kinetics and the metabolites may reach higher concentrations in organisms than their parent compounds. The conversion of molecules from one form to another within an organism often associated with change (increase, decrease, or little change) in pharmacologic activity; refers especially to drugs and other xenobiotics.
Authors and Affiliations
Viny Dave, Praveen Khirwadkar, Kamlesh Dashora
Keywords
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