EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF CANTHIUM PARVIFLORUM BY IN-VITRO METHOD
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 5
Abstract
The present study investigates the anti-inflammatory activity of ethanolic extract of Canthium Parviflorum, is a valuable medicinal shrubby and woody plant which has been valued for centuries in ayurvedic medicine. Phyto-chemical analysis of Canthium parviflorum plant extracts revealed the presence of various bio-chemical compounds such as flavonoids, glycosides, alkaloids, saponins and terpinoids. Since terpenoids and flavonoids have remarkable anti-inflammatory activity, our present work aims at evaluating the in-vitro anti-inflammatory activity of Canthium parviflorum by protein denaturation method. Denaturation of proteins is a well documented cause of inflammation and rheumatoid arthritis. Several anti-inflammatory drugs have shown dose dependent ability to inhibit thermally induced protein denaturation. Ability of CPE extract to bring down thermal denaturation of protein is possibly a contributing factor for its anti-inflammatory activity. The data of our studies suggests that CPE extract showed significant anti-inflammatory activity. Therefore our studies support the isolation and use of active constituents of Canthium parviflorum in treating inflammation.
Authors and Affiliations
Kandikattu Karthik, Bharath Rathna Kumar P, Venu Priya R, Sunil Kumar K , Ranjith Singh. B. Rathore
Keywords
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