EFFECT OF METHANOLIC EXTRACT OF ADENANTHERA PAVONINA LINN ON DALTON'S ASCITIC LYMPHOMA
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 1
Abstract
The present study was undertaken to examine anticancer activity of Adenanthera pavonina L stem bark extract on Dalton's ascitic lymphoma (DAL) in male Swiss albino mice. Tumour was induced in mice by intraperitoneal injection of DAL cells (1 x 1000000 cells / mouse). Methanol extract of Adenanthera pavonina L (MAP) was administrated to the mice at the dose of 125 and 250 mg/kg/day, p.o. The antitumor effect of the extract was evaluated by using In-vitro cytotoxic assay; Mean survival time (MST), Tumour volume (TV), Percentage Increase in Life Span (ILS), viable and non-viable tumour cells count. The findings of this study indicate that the MAP possesses significant antitumor activity.
Authors and Affiliations
Arihara Siva Kumar G, Rajesh Kumar Javvadi1, Vinay Kumar K, Manohar Reddy E, Veera Reddy Y, Harshavardhan G, Akbar MD
Keywords
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