A Review on current scenario of Pharmacosomes
Journal Title: International Journal of Pharmaceutical and Medicinal Reserach - Year 2017, Vol 5, Issue 1
Abstract
Limited permeation into the cells and the adverse effects are the major detriments with most of the drugs used in the chronic disorders. So from the past few decades our focus is on the advanced drug delivery system which can vanquish these problems and vesicular drug delivery system can overcome these problems. Encapsulation of the drug in vesicles increases the existence of the drug in the systemic circulation and reduces the toxicity. Vesicular drug delivery system finds application in immunology, membrane biology and genetic engineering. Pharmacosomes are a type of vesicular system which are defined as the colloidal dispersions of drug covalently bound to lipids and may exist as ultrafine vesicular, micellar or hexagonal aggregates. There has been advancement in the scope of this delivery system for a number of drugs used for inflammation, heart diseases, cancer, and protein delivery along with a large number of herbal drugs. Hence, pharmacosomes open new challenges and opportunities for improved novel vesicular drug delivery system. The present review deals with the review of the research done in the field of pharmacosomes.
Authors and Affiliations
Charanjeet Kaur, Vaishali Goel, Rainu Devi, Aman Kuma, Ujjwal Nautiyal
Keywords
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